Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Feverfew (Tanacetum parthenium) has a long history of use in traditional medicine, particularly in Europe, for the prevention and relief of migraines. The active compounds in feverfew, especially parthenolide, are believed to have anti-inflammatory and vasodilatory properties that may help reduce the frequency and severity of migraine attacks. Scientific studies on feverfew and migraine have produced mixed results. Several randomized controlled trials and meta-analyses have been conducted since the 1980s. Some early studies suggested that feverfew could reduce the frequency of migraine attacks compared to placebo. However, more recent and larger trials have shown either modest benefits or no significant difference from placebo. For example, a 2004 Cochrane review concluded that there is insufficient evidence to recommend feverfew as a reliable treatment for migraine prevention, although some individuals may experience benefit.

Feverfew appears to be generally safe for most people when taken in standard doses, but it can cause side effects such as mouth ulcers, digestive upset, and allergic reactions. Because of the mixed quality and limited quantity of strong evidence, feverfew is sometimes used as an adjunct or alternative treatment for migraine, especially by those seeking herbal options. However, mainstream medical guidelines do not strongly recommend it due to the modest and inconsistent scientific support. Overall, the use of feverfew for migraine is supported by both tradition and some scientific evidence, but the strength of scientific validation is moderate to low.

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