Evidence supporting the use of: Ficus simplicissima
For the health condition: Migraine

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Ficus simplicissima, a species of fig native to parts of Asia, has a history of medicinal use in traditional systems, particularly in some Southeast Asian and Himalayan ethnomedicines. Reports document its use for a variety of ailments, including pain relief and inflammatory conditions, which may indirectly relate to its application for headaches or migraine-like symptoms. However, there is no direct, robust traditional documentation specifying its use exclusively for migraine as defined in modern medicine. Some ethnobotanical surveys (e.g., in Nepal and Vietnam) mention its leaves and latex being used for general pain or as a poultice for headaches, which may be interpreted locally as migraine relief. On the scientific front, there is a lack of clinical or pharmacological studies evaluating Ficus simplicissima specifically for migraine. The plant is known to contain flavonoids and phenolic compounds with potential anti-inflammatory and antioxidant activities, which are theoretically relevant to migraine pathophysiology. Nevertheless, these observations have not been substantiated in migraine-specific models or clinical trials. In summary, the use of Ficus simplicissima for migraine is grounded primarily in traditional practices with limited, low-quality evidence, and there is no substantive scientific validation at present.

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