Evidence supporting the use of: Ginkgo Flavonglycosides
For the health condition: Migraine

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ginkgo flavonglycosides, derived from the leaves of the Ginkgo biloba tree, have been used in traditional medicine systems, particularly in East Asia, for a variety of circulatory and neurological conditions. The rationale for their use in migraine is primarily based on traditional concepts, with some hypothesized mechanisms relating to improved cerebral blood flow and antioxidant activity. However, scientific studies specifically evaluating Ginkgo biloba extract (standardized to contain flavonglycosides) for migraine prevention or treatment are limited and generally of low quality.

A few small clinical trials and open-label studies have explored Ginkgo (sometimes in combination with other herbs like magnesium and coenzyme Q10) for migraine prophylaxis, with mixed and inconclusive results. Systematic reviews and guidelines generally do not recommend Ginkgo as a first-line or evidence-based therapy for migraine, citing insufficient high-quality randomized controlled trials. The biological plausibility for benefit is modest, as the extract may affect platelet-activating factor and vascular tone, but robust clinical validation is lacking.

In summary, while Ginkgo flavonglycosides are traditionally used for headache and circulatory complaints, scientific evidence supporting their efficacy for migraine is weak and inconsistent. More rigorous, well-designed clinical trials would be needed to justify their use for this indication.

More about Ginkgo Flavonglycosides
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Other ingredients used for Migraine

5-Hydroxytryptophan (5-HTP)
alpha-linolenic acid (ALA)
ashwagandha
bergamot
beta caryophyllene
black tea
Indian frankincense
bupleurum falcatum
Chinese salvia root
coenzyme Q10 (CoQ10)
turmeric
curcumin
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
feverfew
fish oil
ginger
ginkgo biloba
gooseberry
gotu kola
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
lavender
luteolin
magnesium
melatonin
moringa
niacin (vitamin B3)
omega-3 fatty acids
Peppermint
phytocannabinoids
pine bark
purple butterbur root
riboflavin (vitamin B2)
specialized pro-resolving mediators (SPMs)
Almond fruit
ubiquinol
valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
zinc
atractylodes
blackboard tree
swertia
Szechuan lovage
chrysanthemum
soursop
1,3,7-Trimethylpurine-2,6-dione
5-methyltetrahydrofolate glucosamine
Apple Cider Vinegar
Albizia
Alpha-Lipoic Acid
Atractylone
Betony
Black Seed
Baikal Skullcap
Beta-hydroxybutyrate
Blepharis
Balsam
Banyan
Brahmi
Butterbur
Bifidobacteria
Black Hellebore
Chinese Silkvine
Crocin
Creatine
Cannabidiol
Corydalis
Carthamus
cola nut
Docosahexaenoic Acid
Danshen
Eicosapentaenoic Acid
Folic Acid
Flavin mononucleotide
Ficus religiosa
Fish
Flavanones
Ficus simplicissima
Frankincense
Goldthread
Gelsemium
Ginkgolides
Ginkgoside
Hellebore
iridoids
Ketone Salts
Kuding tea
lemon balm
Lesser speargrass
Little ironweed
Linalool
Mesua
Methylxanthine
Meadowsweet
Nardostachys
Night jessamine
Osthole
Puerarin
Petasines
Phthalides
Paeoniflorin
Pycnogenol
Polygonum
Palmitoylethanolamide (PEA)
Rue
Rubus
Rauvolfia
Rubiaceae
Spikenard
Sensitive Plant
Salmon Oil
Sandalwood
Scabrous Gentian
Uncaria
Withanolides
Xanthine
Xanthophyll
Xanthone
Yuzu
Zingerone

Products containing Ginkgo Flavonglycosides

We currently have no products on Vitabase that contain this ingredient.