Evidence supporting the use of: Hellebore (unspecified)
For the health condition: Migraine

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Hellebore (unspecified species, but often referring to plants in the genus Helleborus or sometimes Veratrum) has a history of use in traditional medicine, including for neurological conditions like migraine. In ancient Greek and Roman medicine, hellebore was employed as a purgative and for treating a variety of ailments, including headaches and mental disturbances. The use for migraine likely stems from these broader traditional uses for head pain and neurological symptoms. However, hellebore is highly toxic, and its medicinal application was risky and often associated with severe adverse effects.

There is no robust scientific evidence supporting the efficacy or safety of hellebore for treating or preventing migraines. Modern clinical studies have not evaluated hellebore for this indication, and its toxicity profile (including cardiac glycosides and alkaloids) makes it unsuitable and potentially dangerous for such use. Therefore, while there is historical precedent for its use in relation to migraine-like symptoms, this is not backed by modern research, and the traditional use is considered of low evidentiary value due to the lack of supporting data and significant safety concerns.

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