Evidence supporting the use of: Marine lipid (unspecified)
For the health condition: Migraine
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Marine lipids, primarily in the form of omega-3 fatty acids such as EPA and DHA (commonly found in fish oil), have been investigated for their potential role in migraine prevention and management. Several clinical studies and systematic reviews have explored the anti-inflammatory effects of omega-3s, as inflammation is believed to contribute to migraine pathophysiology. Some randomized controlled trials have shown that supplementation with omega-3 fatty acids may modestly reduce the frequency, duration, or severity of migraine attacks in certain individuals, though findings are not universally consistent.
A 2018 systematic review and meta-analysis, for example, suggested that omega-3 supplementation could reduce the frequency of migraine attacks, but the overall effect size was small and the quality of evidence was low to moderate. The mechanism is thought to involve a shift in the balance of pro-inflammatory and anti-inflammatory eicosanoids, as well as modulation of neuronal excitability and vascular function.
However, guidelines from major headache societies do not currently recommend marine lipids as a first-line therapy for migraines, and more robust, large-scale studies are needed to confirm their efficacy. In summary, while there is some scientific evidence supporting the use of marine lipids for migraine, it is limited and not definitive, so the strength of evidence is rated as 2 out of 5.
Other ingredients used for Migraine
5-Hydroxytryptophan (5-HTP)alpha-linolenic acid (ALA)
ashwagandha
bergamot
beta caryophyllene
black tea
Indian frankincense
bupleurum falcatum
Chinese salvia root
coenzyme Q10 (CoQ10)
turmeric
curcumin
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
feverfew
fish oil
ginger
ginkgo biloba
gooseberry
gotu kola
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
lavender
luteolin
magnesium
melatonin
moringa
niacin (vitamin B3)
omega-3 fatty acids
peppermint oil
phytocannabinoids
pine bark
purple butterbur root
riboflavin (vitamin B2)
specialized pro-resolving mediators (SPMs)
almond fruit
ubiquinol
valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
zinc
atractylodes
blackboard tree
swertia
lingusticum wallichii
chrysanthemum
soursop
1,3,7-Trimethylpurine-2,6-dione
5-methyltetrahydrofolate glucosamine
Apple Cider Vinegar
Albizia
Alpha-Lipoic Acid
Acetylsalicylic acid
Atractylone
Betony
Black Seed
Baikal Skullcap
Beta-hydroxybutyrate
Blepharis
Balsam
Banyan
Brahmi
Butterbur
Bifidobacteria
Black Hellebore
Chinese Silkvine
Crocin
Creatine
Cannabidiol
Corydalis
Carthamus
cola nut
Docosahexaenoic Acid
Danshen
Eicosapentaenoic Acid
Folic Acid
Goldthread
Ketone Salts
Little ironweed
Spikenard
Sandalwood
Other health conditions supported by Marine lipid (unspecified)
Alzheimer's DiseaseArthritis
Asthma
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Congestive Heart Failure
Depression
Diabetes
Fatty Liver Disease
Hypertension
Inflammation
Lupus
Macular Degeneration
Memory and Brain Function
Menopause
Migraine
Multiple Sclerosis
Osteoporosis
Psoriasis
Rheumatoid Arthritis
Stress
Triglycerides (high)
Wounds and Sores