Evidence supporting the use of: Puerarin
For the health condition: Migraine

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Puerarin, an isoflavone derived from the root of Pueraria lobata (Kudzu), has a long history in traditional Chinese medicine (TCM), where it is used to treat headaches and related conditions, including migraines. The traditional use is based on its proposed ability to "dispel wind" and "relieve pain," concepts rooted in TCM theory rather than modern pathophysiology. Several TCM formulas containing Kudzu root have been prescribed historically for symptoms compatible with migraine, such as severe, recurring headaches.

Scientific research on puerarin’s efficacy for migraine is limited and largely preclinical. Some animal studies suggest that puerarin may have neuroprotective and vasodilatory effects, and may influence neurotransmitter levels, all of which could theoretically be beneficial in migraine. However, robust clinical trials in humans specifically evaluating puerarin for migraine prevention or treatment are lacking. The evidence, therefore, remains largely anecdotal and traditional, with only preliminary scientific exploration but no firm validation. Most of the available studies are from China and are often of low methodological quality or published in regional journals, making it difficult to draw definitive conclusions about its efficacy for migraines.

In summary, puerarin's use for migraine is primarily justified by traditional practices rather than strong scientific evidence, with a low overall level of support from modern clinical research.

More about Puerarin
More about Migraine

Other ingredients used for Migraine

1,3,7-Trimethylpurine-2,6-dione
5-Hydroxytryptophan (5-HTP)
5-methyltetrahydrofolate glucosamine
Albizia
Almond fruit
alpha-linolenic acid (ALA)
alpha-lipoic acid
apple cider vinegar
ashwagandha
atractylodes
atractylone
Baikal Skullcap
balsam
banyan
bergamot
beta caryophyllene
beta-hydroxybutyrate
betony
Bifidobacteria
Black Hellebore
black seed
black tea
blackboard tree
Blepharis
brahmi
bupleurum falcatum
butterbur
cannabidiol
Carthamus
Chinese salvia root
Chinese silkvine
chrysanthemum
coenzyme Q10 (CoQ10)
cola nut
Corydalis
creatine
crocin
curcumin
danshen
DHA (docosahexaenoic acid)
docosahexaenoic Acid
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
feverfew
Ficus religiosa
Ficus simplicissima
fish
fish oil
flavanones
flavin mononucleotide
folic acid
frankincense
Gelsemium
ginger
ginkgo biloba
ginkgolides
Ginkgoside
goldthread
gooseberry
gotu kola
Hellebore
Indian frankincense
iridoids
ketone salts
kuding tea
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
lavender
lemon balm
Lesser speargrass
linalool
little ironweed
luteolin
magnesium
Meadowsweet
Melatonin
Mesua
Methylxanthine
Moringa
Nardostachys
Niacin (vitamin B3)
Night jessamine
omega-3 fatty acids
Osthole
paeoniflorin
Palmitoylethanolamide (PEA)
Peppermint
Petasines
Phthalides
phytocannabinoids
pine bark
Polygonum
Puerarin
purple butterbur root
Pycnogenol
Rauvolfia
riboflavin (vitamin B2)
Rubiaceae
Rubus
rue
Salmon Oil
Sandalwood
Scabrous Gentian
Sensitive Plant
soursop
specialized pro-resolving mediators (SPMs)
Spikenard
Swertia
Szechuan lovage
turmeric
ubiquinol
Uncaria
Valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
Withanolides
Xanthine
Xanthone
Xanthophyll
Yuzu
Zinc
Zingerone

Products containing Puerarin

We currently have no products on Vitabase that contain this ingredient.