Evidence supporting the use of: Puerarin
For the health condition: Migraine

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Puerarin, an isoflavone derived from the root of Pueraria lobata (Kudzu), has a long history in traditional Chinese medicine (TCM), where it is used to treat headaches and related conditions, including migraines. The traditional use is based on its proposed ability to "dispel wind" and "relieve pain," concepts rooted in TCM theory rather than modern pathophysiology. Several TCM formulas containing Kudzu root have been prescribed historically for symptoms compatible with migraine, such as severe, recurring headaches.

Scientific research on puerarin’s efficacy for migraine is limited and largely preclinical. Some animal studies suggest that puerarin may have neuroprotective and vasodilatory effects, and may influence neurotransmitter levels, all of which could theoretically be beneficial in migraine. However, robust clinical trials in humans specifically evaluating puerarin for migraine prevention or treatment are lacking. The evidence, therefore, remains largely anecdotal and traditional, with only preliminary scientific exploration but no firm validation. Most of the available studies are from China and are often of low methodological quality or published in regional journals, making it difficult to draw definitive conclusions about its efficacy for migraines.

In summary, puerarin's use for migraine is primarily justified by traditional practices rather than strong scientific evidence, with a low overall level of support from modern clinical research.

More about Puerarin
More about Migraine

Other ingredients used for Migraine

5-Hydroxytryptophan (5-HTP)
alpha-linolenic acid (ALA)
ashwagandha
bergamot
beta caryophyllene
black tea
Indian frankincense
bupleurum falcatum
Chinese salvia root
coenzyme Q10 (CoQ10)
turmeric
curcumin
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
feverfew
fish oil
ginger
ginkgo biloba
gooseberry
gotu kola
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
lavender
luteolin
magnesium
melatonin
moringa
niacin (vitamin B3)
omega-3 fatty acids
Peppermint
phytocannabinoids
pine bark
purple butterbur root
riboflavin (vitamin B2)
specialized pro-resolving mediators (SPMs)
Almond fruit
ubiquinol
valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
zinc
atractylodes
blackboard tree
swertia
Szechuan lovage
chrysanthemum
soursop
1,3,7-Trimethylpurine-2,6-dione
5-methyltetrahydrofolate glucosamine
Apple Cider Vinegar
Albizia
Alpha-Lipoic Acid
Atractylone
Betony
Black Seed
Baikal Skullcap
Beta-hydroxybutyrate
Blepharis
Balsam
Banyan
Brahmi
Butterbur
Bifidobacteria
Black Hellebore
Chinese Silkvine
Crocin
Creatine
Cannabidiol
Corydalis
Carthamus
cola nut
Docosahexaenoic Acid
Danshen
Eicosapentaenoic Acid
Folic Acid
Flavin mononucleotide
Ficus religiosa
Fish
Flavanones
Ficus simplicissima
Frankincense
Goldthread
Gelsemium
Ginkgolides
Ginkgoside
Hellebore
iridoids
Ketone Salts
Kuding tea
lemon balm
Lesser speargrass
Little ironweed
Linalool
Mesua
Methylxanthine
Meadowsweet
Nardostachys
Night jessamine
Osthole
Puerarin
Petasines
Phthalides
Paeoniflorin
Pycnogenol
Polygonum
Palmitoylethanolamide (PEA)
Rue
Rubus
Rauvolfia
Rubiaceae
Spikenard
Sensitive Plant
Salmon Oil
Sandalwood
Scabrous Gentian
Uncaria
Withanolides
Xanthine
Xanthophyll
Xanthone
Yuzu
Zingerone

Products containing Puerarin

We currently have no products on Vitabase that contain this ingredient.