Evidence supporting the use of: Rauvolfia
For the health condition: Migraine
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Rauvolfia species, particularly Rauvolfia serpentina, have a long history of use in traditional medicine systems, especially in Ayurveda and other South Asian practices. The plant's roots have been traditionally used for a variety of ailments, including hypertension, anxiety, and as a sedative. Its use for migraine and other headache disorders is primarily based on these traditional practices, where it was believed to calm the nerves and reduce the intensity or frequency of headache attacks.
The principal alkaloid in Rauvolfia, reserpine, is known for its antihypertensive and sedative effects. Some older medical texts and anecdotal reports suggest it was prescribed for migraine relief, likely because of its effects on the nervous system and blood pressure. However, rigorous scientific studies specifically evaluating Rauvolfia or its alkaloids for migraine prevention or treatment are extremely limited or lacking. The available evidence does not meet modern standards for efficacy in migraine management. Furthermore, Rauvolfia and reserpine are associated with significant side effects, such as depression and hypotension, which limits their current clinical use.
In summary, Rauvolfia's use for migraine is justified primarily by traditional and historical usage rather than robust scientific validation. Modern clinical guidelines do not recommend it for migraine, and its risk profile outweighs the uncertain benefits based on current knowledge.
Other ingredients used for Migraine
1,3,7-Trimethylpurine-2,6-dione5-Hydroxytryptophan (5-HTP)
5-methyltetrahydrofolate glucosamine
Albizia
Almond fruit
alpha-linolenic acid (ALA)
alpha-lipoic acid
apple cider vinegar
ashwagandha
atractylodes
atractylone
Baikal Skullcap
balsam
banyan
bergamot
beta caryophyllene
beta-hydroxybutyrate
betony
Bifidobacteria
Black Hellebore
black seed
black tea
blackboard tree
Blepharis
brahmi
bupleurum falcatum
butterbur
cannabidiol
Carthamus
Chinese salvia root
Chinese silkvine
chrysanthemum
coenzyme Q10 (CoQ10)
cola nut
Corydalis
creatine
crocin
curcumin
danshen
DHA (docosahexaenoic acid)
docosahexaenoic Acid
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
feverfew
Ficus religiosa
Ficus simplicissima
fish
fish oil
flavanones
flavin mononucleotide
folic acid
frankincense
Gelsemium
ginger
ginkgo biloba
ginkgolides
Ginkgoside
goldthread
gooseberry
gotu kola
Hellebore
Indian frankincense
iridoids
ketone salts
kuding tea
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
lavender
lemon balm
Lesser speargrass
linalool
little ironweed
luteolin
magnesium
Meadowsweet
Melatonin
Mesua
Methylxanthine
Moringa
Nardostachys
Niacin (vitamin B3)
Night jessamine
omega-3 fatty acids
Osthole
paeoniflorin
Palmitoylethanolamide (PEA)
Peppermint
Petasines
Phthalides
phytocannabinoids
pine bark
Polygonum
Puerarin
purple butterbur root
Pycnogenol
Rauvolfia
riboflavin (vitamin B2)
Rubiaceae
Rubus
rue
Salmon Oil
Sandalwood
Scabrous Gentian
Sensitive Plant
soursop
specialized pro-resolving mediators (SPMs)
Spikenard
Swertia
Szechuan lovage
turmeric
ubiquinol
Uncaria
Valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
Withanolides
Xanthine
Xanthone
Xanthophyll
Yuzu
Zinc
Zingerone
Other health conditions supported by Rauvolfia
AnxietyHypertension
Insomnia
Migraine
Schizophrenia
Stress
