Evidence supporting the use of: Rubiaceae
For the health condition: Migraine

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

The use of Rubiaceae family plants for the treatment of migraine is primarily rooted in traditional medicine systems rather than robust scientific evidence. Several genera within Rubiaceae, such as Coffea (coffee) and Cinchona (source of quinine), have a history of medicinal use, but specific references to their use for migraine are largely ethnobotanical and anecdotal. For example, in some traditional practices, extracts from Rubia (madder), Morinda, or other Rubiaceae members have been used for general pain relief or as anti-inflammatory agents, which could be extrapolated to headache or migraine treatment. However, these uses are based on historical herbal medicine records and local traditions rather than controlled clinical studies.

There is limited preclinical research suggesting that some Rubiaceae species contain compounds with potential anti-inflammatory or analgesic properties, but these findings are not directly linked to migraine management, and no high-quality clinical trials have established efficacy or safety for this indication. In summary, while there is a traditional basis for using certain Rubiaceae plants for headaches or migraine-like symptoms, the scientific evidence remains weak, justifying a low evidence rating.

More about Rubiaceae
More about Migraine

Other ingredients used for Migraine

1,3,7-Trimethylpurine-2,6-dione
5-Hydroxytryptophan (5-HTP)
5-methyltetrahydrofolate glucosamine
Albizia
Almond fruit
alpha-linolenic acid (ALA)
alpha-lipoic acid
apple cider vinegar
ashwagandha
atractylodes
atractylone
Baikal Skullcap
balsam
banyan
bergamot
beta caryophyllene
beta-hydroxybutyrate
betony
Bifidobacteria
Black Hellebore
black seed
black tea
blackboard tree
Blepharis
brahmi
bupleurum falcatum
butterbur
cannabidiol
Carthamus
Chinese salvia root
Chinese silkvine
chrysanthemum
coenzyme Q10 (CoQ10)
cola nut
Corydalis
creatine
crocin
curcumin
danshen
DHA (docosahexaenoic acid)
docosahexaenoic Acid
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
feverfew
Ficus religiosa
Ficus simplicissima
fish
fish oil
flavanones
flavin mononucleotide
folic acid
frankincense
Gelsemium
ginger
ginkgo biloba
ginkgolides
Ginkgoside
goldthread
gooseberry
gotu kola
Hellebore
Indian frankincense
iridoids
ketone salts
kuding tea
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
lavender
lemon balm
Lesser speargrass
linalool
little ironweed
luteolin
magnesium
Meadowsweet
Melatonin
Mesua
Methylxanthine
Moringa
Nardostachys
Niacin (vitamin B3)
Night jessamine
omega-3 fatty acids
Osthole
paeoniflorin
Palmitoylethanolamide (PEA)
Peppermint
Petasines
Phthalides
phytocannabinoids
pine bark
Polygonum
Puerarin
purple butterbur root
Pycnogenol
Rauvolfia
riboflavin (vitamin B2)
Rubiaceae
Rubus
rue
Salmon Oil
Sandalwood
Scabrous Gentian
Sensitive Plant
soursop
specialized pro-resolving mediators (SPMs)
Spikenard
Swertia
Szechuan lovage
turmeric
ubiquinol
Uncaria
Valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
Withanolides
Xanthine
Xanthone
Xanthophyll
Yuzu
Zinc
Zingerone

Products containing Rubiaceae

We currently have no products on Vitabase that contain this ingredient.