Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Soursop (Annona muricata), also known as graviola or guanábana, is a tropical fruit-bearing tree whose leaves, fruit, and other parts have been used in traditional medicine systems, particularly in the Caribbean, Central America, and parts of Africa and Asia. In these traditions, soursop has been used for a variety of ailments, including pain relief, fever reduction, and as a remedy for headaches and migraines. However, the evidence supporting its effectiveness specifically for migraine is largely anecdotal and based on traditional knowledge rather than rigorous scientific studies.

Some traditional practitioners prepare soursop leaf teas or infusions to help alleviate pain or headaches, attributing the effect to the plant's purported anti-inflammatory and analgesic properties. While laboratory research has shown that soursop contains bioactive compounds such as acetogenins, alkaloids, and phenols, which may have anti-inflammatory or antioxidant effects, there is currently insufficient clinical evidence directly linking soursop consumption or supplementation to migraine relief in humans. No controlled trials or robust human studies have been published to confirm its efficacy for this specific condition. Therefore, the use of soursop for migraine is primarily justified by traditional use, and the supporting evidence is weak (rated 1 out of 5).

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