Evidence supporting the use of: Vitamin B2 (riboflavin selenite)
For the health condition: Migraine

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin B2 (riboflavin) is supported by scientific evidence for use in migraine prophylaxis. Clinical studies, including randomized controlled trials, have shown that high-dose riboflavin (usually 400 mg daily) can reduce the frequency and duration of migraine attacks in some individuals. Riboflavin is involved in mitochondrial energy production, and its supplementation is believed to improve mitochondrial dysfunction, a factor implicated in the pathophysiology of migraines. The American Academy of Neurology and the American Headache Society have both recognized riboflavin as "probably effective" for migraine prevention based on available evidence.

It is important to clarify that riboflavin selenite is not a standard form; the commonly studied form is riboflavin (vitamin B2) itself. No credible studies support the use of a riboflavin-selenium combination (selenite) specifically for migraines. The benefit is attributed to riboflavin alone. Overall, the evidence base is moderate to strong, with some systematic reviews and meta-analyses supporting its efficacy and good tolerability in both adults and children. Dosages used in studies are much higher than what is found in standard multivitamins.

In summary, riboflavin is scientifically validated for migraine prophylaxis, with a solid evidence base, but the selenite form is not specifically studied for this condition.

More about Vitamin B2 (riboflavin selenite)
More about Migraine

Other health conditions supported by Vitamin B2 (riboflavin selenite)

Cataracts
Dermatitis
Fatigue
Headache (general)
Headache (tension)
Migraine

Products containing Vitamin B2 (riboflavin selenite)

We currently have no products on Vitabase that contain this ingredient.