Algae, particularly species like spirulina and chlorella, have garnered interest for their potential to support mitochondrial health. The scientific rationale stems from algae's rich nutritional profile, which includes high levels of antioxidants (such as phycocyanin in spirulina), vitamins, minerals, and polyunsaturated fatty acids. These compounds are thought to combat oxidative stress, a key factor in mitochondrial dysfunction. Some laboratory and animal studies suggest that spirulina and related algae can enhance mitochondrial function, reduce oxidative damage, and improve cellular energy (ATP) production. For example, research published in Oxidative Medicine and Cellular Longevity (2013) demonstrated that spirulina supplementation improved mitochondrial integrity and reduced oxidative stress markers in animal models.

However, direct evidence in humans is limited and often indirect. Most human studies focus on general antioxidant effects, anti-inflammatory properties, or improvements in exercise performance, rather than direct measurements of mitochondrial function. Systematic reviews conclude that while the nutritional components of algae theoretically benefit mitochondrial health, high-quality clinical trials specifically addressing this mechanism are lacking. Therefore, while the use of algae to support mitochondrial function is scientifically plausible and supported by basic research, the direct human evidence remains preliminary.