Evidence supporting the use of: Antioxidant (unspecified)
For the body system: Mitochondria

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Antioxidants are widely studied for their potential to support mitochondrial health. Mitochondria are the primary sites of cellular energy (ATP) production and are vulnerable to oxidative damage from reactive oxygen species (ROS), which are byproducts of normal metabolism. Accumulation of ROS can lead to mitochondrial dysfunction, contributing to aging and various diseases. The use of antioxidants aims to neutralize ROS and protect mitochondrial integrity.

Scientific studies, mostly in vitro and in animal models, have shown that antioxidants such as coenzyme Q10, alpha-lipoic acid, and certain polyphenols can improve mitochondrial function, decrease oxidative stress, and enhance cellular energy production. Some clinical studies in humans suggest that specific antioxidants (e.g., coenzyme Q10) may benefit mitochondrial disorders and age-related decline, but the evidence is less robust for generic or unspecified antioxidants. Reviews (e.g., Antioxidants & Redox Signaling, 2017) highlight both the promise and limitations: while some antioxidants can target mitochondria and exert protective effects, results are inconsistent, and benefits often depend on the type of antioxidant and specific health condition.

Overall, there is a scientific basis for the use of certain antioxidants to support mitochondrial health, but the evidence for “antioxidant (unspecified)” is moderate and not definitive. More targeted research is needed to clarify which antioxidants, at what doses, and in which populations, are effective for supporting mitochondrial function.

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Other ingredients that support Mitochondria

7-Keto-DHEA
acetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
bovine liver
caffeine
catechins
citicoline
coenzyme Q10 (CoQ10)
coffee fruit
copper
creatine monohydrate
d-alpha tocopherol
epigallocatechin gallate (EGCG)
fisetin
fish oil
flavonols
fructose
fruit and vegetable blend (proprietary)
glycerophosphocholine (GPC)
gooseberry
grape
greens blend (proprietary)
hesperetin
knotweed
krill oil
l-carnitine
l-carnosine
l-citrulline
l-glutathione
l-glycine
l-taurine
lentinula edodes mycelia
linoleic acid (LA)
liquid liver fractions
luteolin
mackerel
magnesium
maitake mushroom
malic acid
maltodextrin
maltose
manganese
maqui berry
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
moringa
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oleanolic acid
pantethine
pantothenic acid (vitamin B5)
phenolic acids
phosphatidylcholine
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
quercetin
quinoa
resveratrol
rhodiola
riboflavin (vitamin B2)
rosemary
sardines
selenium
black ginger
spinach
starch
stearic acid
strawberry
succinic acid
sulforaphane glucosinolate
thiamin (vitamin B1)
tocotrienols
trans-geranylgeraniol
trans-pterostilbene
tributyrin
turkey tail mushroom
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
vitamin B
vitamin B
vitamin D3
water
watermelon
β-nicotinamide mononucleotide (NMN)
lingzhi
cistanche
ganoderma
electrolytes blend (proprietary)
polyphenols
trace minerals
fulvic acid
goji berry
herbal blend (proprietary)
algae
AMP-activated protein kinase (AMPK)
thyroid substance
ashitaba
1,3,7-Trimethylpurine-2,6-dione
5-Aminoimidazole-4-Carboxamide Ribonucleotide
Alpha polylactate
Apigenin
Alpha-Lipoic Acid
Ampelopsin
adenosine triphosphate (ATP)
Animal protein
Beta-hydroxybutyrate
Beef liver
berry
Caffeic Acid
Centrophenoxine
Camellia sinensis
Cardarine
Cocarboxylase
Capsinoids
Coenzyme A
Cardiolipin
Cyanidin
Capsiate
Chocolate
Creatine
C-Phycocyanin
Dihydrolipoic Acid
D-Ribose
Eriocitrin
Ergothioneine
glucose
Ketone Salts

Products containing Antioxidant (unspecified)

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