Evidence supporting the use of: Beef liver
For the body system: Mitochondria
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Beef liver is used to support mitochondrial health primarily due to its dense nutritional profile, which scientific research supports as beneficial for mitochondrial function. Beef liver is exceptionally rich in nutrients essential for mitochondrial energy production, including B vitamins (notably B2, B3, B5, B6, B12), iron, copper, and Coenzyme Q10 (CoQ10). Several studies emphasize the role of B vitamins and CoQ10 in mitochondrial bioenergetics: B vitamins serve as cofactors in the Krebs cycle and electron transport chain, while CoQ10 is a critical component of the mitochondrial respiratory chain, facilitating ATP production. Iron and copper are also required for the synthesis of cytochromes and other proteins involved in electron transfer. Deficiencies in these nutrients have been associated with impaired mitochondrial function and increased oxidative stress. While beef liver contains all these nutrients in bioavailable forms, there is limited direct evidence from clinical trials that beef liver supplementation specifically enhances mitochondrial function in humans. Most evidence is extrapolated from studies on individual nutrients rather than whole food interventions. Still, the established roles of these nutrients provide a rationale for beef liver’s use in supporting mitochondrial health. Thus, the use is scientifically plausible and supported indirectly, but direct clinical evidence is limited, warranting a moderate rating.
Other ingredients that support Mitochondria
1,3,7-Trimethylpurine-2,6-dione5-Aminoimidazole-4-Carboxamide Ribonucleotide
7-Keto-DHEA
Acetyl L-carnitine
adenosine 5-triphosphate disodium (ATP)
Adenosine triphosphate (ATP)
Algae
Alpha polylactate
alpha-ketoglutarate (AKG)
alpha-lipoic acid
amino acids
AMP-activated protein kinase (AMPK)
ampelopsin
animal protein
apigenin
ashitaba
ashwagandha
Beef liver
berry
beta-hydroxybutyrate
black ginger
bovine liver
C-phycocyanin
caffeic Acid
caffeine
Camellia sinensis
capsiate
capsinoids
cardarine
cardiolipin
catechins
centrophenoxine
chocolate
cistanche
citicoline
cocarboxylase
Coenzyme A
coenzyme Q10 (CoQ10)
coffee fruit
copper
creatine
creatine monohydrate
cyanidin
d-alpha tocopherol
D-Ribose
dihydrolipoic acid
electrolytes blend (proprietary)
epigallocatechin gallate (EGCG)
ergothioneine
eriocitrin
fatty acids
fisetin
fish
fish oil
flavin mononucleotide
flavones
flavonols
fruit and vegetable blend (proprietary)
fucoxanthin
fulvic acid
fungus
gamma-glutamylcysteine
ganoderma
geranylgeraniol
Ginsenosides
glucose
Glutathione
glycerophosphocholine (GPC)
goji berry
gooseberry
grape
greens blend (proprietary)
guanidinopropionic acid (GPA )
Haematococcus pluvialis
herbal blend (proprietary)
hesperetin
Honokiol
Idebenone
inosine
Kaempferide
Kaempferol
ketone salts
knotweed
krill oil
l-carnitine
L-carnosine
L-citrulline
L-glutathione
L-glycine
L-taurine
Lentinula edodes mycelia
lingzhi
linoleic acid (LA)
lipids
liquid liver fractions
luteolin
magnesium
maitake mushroom
malic acid
manganese
maqui berry
Marine fat
Marine lipid
Matcha
medium chain triglycerides (MCT)
Melatonin
Methoxy-substituted benzoquinones
Methylxanthine
Moringa
Mushroom
Myricetin
NADH
Nannochloropsis
Naringenin
Niacin (vitamin B3)
Niacinamide (vitamin B3)
nicotinamide riboside
Nobiletin
oleanolic acid
Oleoyl-phosphatidylethanolamine
oxaloacetic acid
oxidase
pantethine
pantothenic acid (vitamin B5)
paraxanthine
phenolic compounds
phosphatidylcholine
Phosphatidylethanolamine
Phosphocreatine
Phytoplankton
Polydatin
polyphenols
Propionyl-L-Carnitine
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
pyrroloquinoline quinone
pyruvate
quercetin
quinoa
quinone
resveratrol
Rhodiola
riboflavin (vitamin B2)
ribose
Ribose-l-cysteine
Rosarin
rosavins
rosemary
Salidroside
Schisandrins
selenium
Selenocysteine
Shilajit
spinach
Stilbenoid
strawberry
succinic acid
Sulforaphane
sulforaphane glucosinolate
Taxifolin
Tetradecylthioacetic acid
Thiamin (vitamin B1)
thyroid substance
tocotrienols
trace minerals
Trans-geranylgeraniol
Trans-pterostilbene
Triacetyluridine
tributyrin
Turkey tail mushroom
ubiquinol
Uridine
Urolithin A
vegetable and fruit blend (proprietary)
vitamin B
vitamin B
vitamin D3
Watermelon
Withanolides
β-nicotinamide mononucleotide (NMN)