Evidence supporting the use of: Berry
For the body system: Mitochondria
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Berries—including blueberries, strawberries, raspberries, blackberries, and others—have been investigated for their potential to support mitochondrial health, mainly due to their high polyphenol, flavonoid, and antioxidant content. Scientific studies, primarily in vitro and animal models, suggest that berry extracts and their bioactive compounds (such as anthocyanins and resveratrol) can improve mitochondrial function by reducing oxidative stress, enhancing mitochondrial biogenesis, and protecting against mitochondrial dysfunction. For example, research has shown that blueberry supplementation in rodents enhances markers of mitochondrial biogenesis and reduces markers of oxidative damage in brain and muscle tissues. Some studies in cell cultures demonstrate that berry-derived polyphenols can upregulate pathways such as PGC-1α and SIRT1, which are critical regulators of mitochondrial biogenesis and function.
However, while these mechanisms are promising, robust clinical studies in humans are limited. Most evidence remains preclinical, and results from human trials are preliminary, often focusing on general health markers rather than direct mitochondrial outcomes. Nonetheless, the antioxidant and anti-inflammatory properties of berries are well established, supporting their potential role in maintaining mitochondrial health. Overall, the scientific basis is plausible but not yet definitive, and more rigorous human studies are needed to confirm efficacy.
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7-Keto-DHEA
Acetyl L-carnitine
adenosine 5-triphosphate disodium (ATP)
Adenosine triphosphate (ATP)
Algae
Alpha polylactate
alpha-ketoglutarate (AKG)
alpha-lipoic acid
amino acids
AMP-activated protein kinase (AMPK)
ampelopsin
animal protein
apigenin
ashitaba
ashwagandha
Beef liver
berry
beta-hydroxybutyrate
black ginger
bovine liver
C-phycocyanin
caffeic Acid
caffeine
Camellia sinensis
capsiate
capsinoids
cardarine
cardiolipin
catechins
centrophenoxine
chocolate
cistanche
citicoline
cocarboxylase
Coenzyme A
coenzyme Q10 (CoQ10)
coffee fruit
copper
creatine
creatine monohydrate
cyanidin
d-alpha tocopherol
D-Ribose
dihydrolipoic acid
electrolytes blend (proprietary)
epigallocatechin gallate (EGCG)
ergothioneine
eriocitrin
fatty acids
fisetin
fish
fish oil
flavin mononucleotide
flavones
flavonols
fruit and vegetable blend (proprietary)
fucoxanthin
fulvic acid
fungus
gamma-glutamylcysteine
ganoderma
geranylgeraniol
Ginsenosides
glucose
Glutathione
glycerophosphocholine (GPC)
goji berry
gooseberry
grape
greens blend (proprietary)
guanidinopropionic acid (GPA )
Haematococcus pluvialis
herbal blend (proprietary)
hesperetin
Honokiol
Idebenone
inosine
Kaempferide
Kaempferol
ketone salts
knotweed
krill oil
l-carnitine
L-carnosine
L-citrulline
L-glutathione
L-glycine
L-taurine
Lentinula edodes mycelia
lingzhi
linoleic acid (LA)
lipids
liquid liver fractions
luteolin
magnesium
maitake mushroom
malic acid
manganese
maqui berry
Marine fat
Marine lipid
Matcha
medium chain triglycerides (MCT)
Melatonin
Methoxy-substituted benzoquinones
Methylxanthine
Moringa
Mushroom
Myricetin
NADH
Nannochloropsis
Naringenin
Niacin (vitamin B3)
Niacinamide (vitamin B3)
nicotinamide riboside
Nobiletin
oleanolic acid
Oleoyl-phosphatidylethanolamine
oxaloacetic acid
oxidase
pantethine
pantothenic acid (vitamin B5)
paraxanthine
phenolic compounds
phosphatidylcholine
Phosphatidylethanolamine
Phosphocreatine
Phytoplankton
Polydatin
polyphenols
Propionyl-L-Carnitine
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
pyrroloquinoline quinone
pyruvate
quercetin
quinoa
quinone
resveratrol
Rhodiola
riboflavin (vitamin B2)
ribose
Ribose-l-cysteine
Rosarin
rosavins
rosemary
Salidroside
Schisandrins
selenium
Selenocysteine
Shilajit
spinach
Stilbenoid
strawberry
succinic acid
Sulforaphane
sulforaphane glucosinolate
Taxifolin
Tetradecylthioacetic acid
Thiamin (vitamin B1)
thyroid substance
tocotrienols
trace minerals
Trans-geranylgeraniol
Trans-pterostilbene
Triacetyluridine
tributyrin
Turkey tail mushroom
ubiquinol
Uridine
Urolithin A
vegetable and fruit blend (proprietary)
vitamin B
vitamin B
vitamin D3
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Withanolides
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