Evidence supporting the use of: Berry
For the body system: Mitochondria

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Berries—including blueberries, strawberries, raspberries, blackberries, and others—have been investigated for their potential to support mitochondrial health, mainly due to their high polyphenol, flavonoid, and antioxidant content. Scientific studies, primarily in vitro and animal models, suggest that berry extracts and their bioactive compounds (such as anthocyanins and resveratrol) can improve mitochondrial function by reducing oxidative stress, enhancing mitochondrial biogenesis, and protecting against mitochondrial dysfunction. For example, research has shown that blueberry supplementation in rodents enhances markers of mitochondrial biogenesis and reduces markers of oxidative damage in brain and muscle tissues. Some studies in cell cultures demonstrate that berry-derived polyphenols can upregulate pathways such as PGC-1α and SIRT1, which are critical regulators of mitochondrial biogenesis and function.

However, while these mechanisms are promising, robust clinical studies in humans are limited. Most evidence remains preclinical, and results from human trials are preliminary, often focusing on general health markers rather than direct mitochondrial outcomes. Nonetheless, the antioxidant and anti-inflammatory properties of berries are well established, supporting their potential role in maintaining mitochondrial health. Overall, the scientific basis is plausible but not yet definitive, and more rigorous human studies are needed to confirm efficacy.

More about berry
More about Mitochondria

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hesperetin
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l-carnitine
l-carnosine
l-citrulline
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l-glycine
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linoleic acid (LA)
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niacin (vitamin B3)
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pantethine
pantothenic acid (vitamin B5)
phenolic acids
phosphatidylcholine
pyridoxal-5-phosphate (P-5-P)
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quercetin
quinoa
resveratrol
rhodiola
riboflavin (vitamin B2)
rosemary
sardines
selenium
black ginger
spinach
starch
stearic acid
strawberry
succinic acid
sulforaphane glucosinolate
thiamin (vitamin B1)
tocotrienols
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ubiquinol
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Caffeic Acid
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Products containing berry

We currently have no products on Vitabase that contain this ingredient.