Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bovine liver is recognized for its rich nutrient profile, particularly its high content of B vitamins (such as B2, B3, B5, B6, B9, and B12), iron, and coenzyme Q10 (CoQ10). These nutrients are directly involved in mitochondrial function and energy metabolism. For example, B vitamins act as cofactors in the mitochondrial electron transport chain and Krebs cycle, both essential for cellular energy (ATP) production. CoQ10, found in meaningful amounts in liver, is a crucial component of the mitochondrial respiratory chain and supports ATP synthesis. Iron is critical for the formation of cytochromes, which are involved in electron transport within mitochondria.

Several studies have demonstrated that deficiencies in these nutrients can impair mitochondrial function and energy production. While there are few direct clinical trials on bovine liver supplementation for improving mitochondrial health, the established role of its constituent nutrients provides a scientific rationale for its use. Animal-derived organs like liver have traditionally been recommended in ancestral diets for energy and vitality, though such traditions are secondary to the modern scientific understanding of nutrient-mitochondria relationships.

Therefore, while bovine liver is not a targeted mitochondrial therapy, its nutrient density—especially in compounds essential for mitochondrial activity—offers a scientifically supported basis for its use to support mitochondrial health. However, direct human clinical evidence is limited, and most claims are extrapolated from the known functions of its nutrients.

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