Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Carnitine Orotate is a compound formed from carnitine and orotic acid. Carnitine itself is well-recognized for its role in mitochondrial function, particularly in the transport of long-chain fatty acids into mitochondria for beta-oxidation and energy production. There is scientific evidence that supplemental L-carnitine can support mitochondrial health and energy metabolism, especially in cases of deficiency or certain metabolic conditions. Orotic acid, meanwhile, is involved in nucleotide synthesis but is not known to directly impact mitochondrial function.

However, specific studies on carnitine orotate (as opposed to L-carnitine or other forms) and its effects on mitochondrial function are limited. A few animal studies suggest that carnitine orotate may have hepatoprotective and metabolic benefits, potentially supporting mitochondrial function in liver cells. For example, some research in rodents indicates improved fatty acid metabolism and reduced liver damage under stress conditions. Yet, robust clinical trials in humans are lacking, and there is limited direct evidence specifically linking carnitine orotate to overall mitochondrial support in humans.

In summary, while the underlying logic of delivering carnitine to support the mitochondria is scientifically valid, and there are some preclinical data on carnitine orotate, direct scientific validation for the use of carnitine orotate specifically to support the mitochondrial body system is modest and not well-established. More research is needed to confirm efficacy in humans.

More about Carnitine Orotate
More about Mitochondria

Other ingredients that support Mitochondria

7-Keto-DHEA
acetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
bovine liver
caffeine
catechins
citicoline
coenzyme Q10 (CoQ10)
coffee fruit
copper
creatine monohydrate
d-alpha tocopherol
epigallocatechin gallate (EGCG)
fisetin
fish oil
flavonols
fructose
fruit and vegetable blend (proprietary)
glycerophosphocholine (GPC)
gooseberry
grape
greens blend (proprietary)
hesperetin
knotweed
krill oil
l-carnitine
l-carnosine
l-citrulline
l-glutathione
l-glycine
l-taurine
lentinula edodes mycelia
linoleic acid (LA)
liquid liver fractions
luteolin
mackerel
magnesium
maitake mushroom
malic acid
maltodextrin
maltose
manganese
maqui berry
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
moringa
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oleanolic acid
pantethine
pantothenic acid (vitamin B5)
phenolic acids
phosphatidylcholine
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
quercetin
quinoa
resveratrol
rhodiola
riboflavin (vitamin B2)
rosemary
sardines
selenium
black ginger
spinach
starch
stearic acid
strawberry
succinic acid
sulforaphane glucosinolate
thiamin (vitamin B1)
tocotrienols
trans-geranylgeraniol
trans-pterostilbene
tributyrin
turkey tail mushroom
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
vitamin B
vitamin B
vitamin D3
water
watermelon
β-nicotinamide mononucleotide (NMN)
lingzhi
cistanche
ganoderma
electrolytes blend (proprietary)
polyphenols
trace minerals
fulvic acid
goji berry
herbal blend (proprietary)
algae
AMP-activated protein kinase (AMPK)
thyroid substance
ashitaba
1,3,7-Trimethylpurine-2,6-dione
5-Aminoimidazole-4-Carboxamide Ribonucleotide
Alpha polylactate
Apigenin
Alpha-Lipoic Acid
Ampelopsin
adenosine triphosphate (ATP)
Animal protein
Beta-hydroxybutyrate
Beef liver
berry
Caffeic Acid
Centrophenoxine
Camellia sinensis
Cardarine
Cocarboxylase
Capsinoids
Coenzyme A
Cardiolipin
Cyanidin
Capsiate
Chocolate
Creatine
C-Phycocyanin
Dihydrolipoic Acid
D-Ribose
Eriocitrin
Ergothioneine
glucose
Ketone Salts

Other body systems supported by Carnitine Orotate

Heart
Mitochondria

Products containing Carnitine Orotate

We currently have no products on Vitabase that contain this ingredient.