Centrophenoxine (also known as meclofenoxate) has been studied primarily for its nootropic and anti-aging effects, particularly in relation to brain health. There is some scientific evidence suggesting that Centrophenoxine can support mitochondrial function, mostly based on animal studies and limited human research. The compound is believed to enhance cellular energy metabolism by increasing the uptake of glucose and oxygen in brain cells, and by promoting the removal of lipofuscin, a cellular waste product that accumulates with age and can impair mitochondrial function.

Experimental studies in rodents have shown that Centrophenoxine may improve mitochondrial membrane potential and reduce oxidative stress, both of which are important for maintaining healthy mitochondrial activity. Some studies suggest that it can enhance the production of ATP (adenosine triphosphate), the cell's primary energy molecule, by supporting mitochondrial efficiency. However, direct evidence in humans is limited, and most clinical studies have focused on cognitive outcomes rather than direct mitochondrial parameters.

Overall, while there is some scientific rationale and preclinical evidence for Centrophenoxine’s support of mitochondrial function, robust human data are lacking. The evidence is not as strong or direct as for other mitochondrial support agents, but its use is based on more than just tradition or anecdote.