Evidence supporting the use of: Coenzyme Q10
For the body system: Mitochondria
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Coenzyme Q10 (CoQ10), also known as ubiquinone, is a vitamin-like compound that plays a crucial role in mitochondrial function. It is an essential component of the electron transport chain, which is responsible for producing ATP—the main energy currency in cells. Scientific evidence supports the use of CoQ10 for supporting mitochondrial health, particularly in conditions where mitochondrial dysfunction is implicated, such as in certain neurodegenerative diseases, cardiovascular disorders, and age-related decline in cellular energy production.
Multiple clinical trials and meta-analyses have demonstrated that CoQ10 supplementation can improve mitochondrial bioenergetics by enhancing ATP production and reducing oxidative stress within mitochondria. For example, studies in patients with mitochondrial myopathies, heart failure, and Parkinson’s disease have shown modest benefits in symptoms and biochemical markers of mitochondrial function. CoQ10 is also widely recognized for its antioxidant properties, helping to protect mitochondrial membranes from oxidative damage.
While more research is needed to fully define its therapeutic scope, the current body of scientific literature provides a strong theoretical and experimental basis for using CoQ10 as a mitochondrial support supplement, especially in populations with documented CoQ10 deficiency or impaired mitochondrial function.
Other ingredients that support Mitochondria
7-Keto-DHEAacetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
bovine liver
caffeine
catechins
citicoline
coenzyme Q10 (CoQ10)
coffee fruit
copper
creatine monohydrate
d-alpha tocopherol
epigallocatechin gallate (EGCG)
fisetin
fish oil
flavonols
fructose
fruit and vegetable blend (proprietary)
glycerophosphocholine (GPC)
gooseberry
grape
greens blend (proprietary)
hesperetin
knotweed
krill oil
l-carnitine
l-carnosine
l-citrulline
l-glutathione
l-glycine
l-taurine
lentinula edodes mycelia
linoleic acid (LA)
liquid liver fractions
luteolin
mackerel
magnesium
maitake mushroom
malic acid
maltodextrin
maltose
manganese
maqui berry
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
moringa
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oleanolic acid
pantethine
pantothenic acid (vitamin B5)
phenolic acids
phosphatidylcholine
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
quercetin
quinoa
resveratrol
rhodiola
riboflavin (vitamin B2)
rosemary
sardines
selenium
black ginger
spinach
starch
stearic acid
strawberry
succinic acid
sulforaphane glucosinolate
thiamin (vitamin B1)
tocotrienols
trans-geranylgeraniol
trans-pterostilbene
tributyrin
turkey tail mushroom
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
vitamin B
vitamin B
vitamin D3
water
watermelon
β-nicotinamide mononucleotide (NMN)
lingzhi
cistanche
ganoderma
electrolytes blend (proprietary)
polyphenols
trace minerals
fulvic acid
goji berry
herbal blend (proprietary)
algae
AMP-activated protein kinase (AMPK)
thyroid substance
ashitaba
1,3,7-Trimethylpurine-2,6-dione
5-Aminoimidazole-4-Carboxamide Ribonucleotide
Alpha polylactate
Apigenin
Alpha-Lipoic Acid
Ampelopsin
adenosine triphosphate (ATP)
Animal protein
Beta-hydroxybutyrate
Beef liver
berry
Caffeic Acid
Centrophenoxine
Camellia sinensis
Cardarine
Cocarboxylase
Capsinoids
Coenzyme A
Cardiolipin
Cyanidin
Capsiate
Chocolate
Creatine
C-Phycocyanin
Dihydrolipoic Acid
D-Ribose
Eriocitrin
Ergothioneine
glucose
Ketone Salts
Other body systems supported by Coenzyme Q10
ArteriesBlood
Brain
Circulatory System
Gums
Heart
Immune System
Kidneys
Liver
Mitochondria
Muscles
Nerves
Reproductive System
Skin