Evidence supporting the use of: Cyanidin
For the body system: Mitochondria

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cyanidin is an anthocyanin, a type of flavonoid commonly found in various fruits and vegetables, particularly berries. There is emerging scientific interest in cyanidin's potential to support mitochondrial function due to its antioxidant properties. Several in vitro and animal studies have shown that cyanidin and its glycosides can reduce oxidative stress, which is known to impair mitochondrial efficiency and integrity. For example, research has demonstrated that cyanidin-3-glucoside can enhance mitochondrial biogenesis and protect against mitochondrial dysfunction in models of metabolic syndrome and neurodegenerative diseases. These effects are generally attributed to the compound’s ability to modulate oxidative stress pathways and activate signaling molecules such as AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), both of which are important regulators of mitochondrial health. However, robust clinical evidence in humans is still limited. Most available data are derived from preclinical studies, and the translation of these findings to human health outcomes remains uncertain. Therefore, while there is a scientific rationale and preliminary evidence for the use of cyanidin to support mitochondrial function, the current level of evidence is modest and further high-quality human studies are needed to confirm its efficacy.

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Products containing cyanidin

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