Evidence supporting the use of: Lipids
For the body system: Mitochondria

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Lipids play a crucial role in supporting mitochondrial function, and their use for this purpose is strongly supported by scientific evidence. Mitochondria are the primary organelles for energy production in cells, generating ATP through oxidative phosphorylation. The mitochondrial membranes, particularly the inner membrane, are composed largely of phospholipids and specific lipid types such as cardiolipin. These lipids are essential for maintaining mitochondrial structure, fluidity, and the proper functioning of protein complexes involved in the electron transport chain.

Research shows that deficiencies or imbalances in mitochondrial lipids, especially cardiolipin, can impair mitochondrial bioenergetics and are linked to various diseases, including Barth syndrome and neurodegenerative disorders. Supplementation with certain lipids, such as phospholipids (e.g., phosphatidylcholine) and omega-3 fatty acids, has been shown in some studies to improve mitochondrial membrane composition and function. For example, omega-3 fatty acids can enhance mitochondrial biogenesis and efficiency, while phospholipids can help repair damaged mitochondrial membranes.

Therefore, the use of lipids to support mitochondrial health is scientifically grounded, with a strong mechanistic basis and growing evidence from both basic research and clinical studies. However, the evidence is not yet conclusive for all types of lipids or all health conditions, so the rating is 4 out of 5.

More about Lipids
More about Mitochondria

Other ingredients that support Mitochondria

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acetyl l-carnitine
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alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
bovine liver
caffeine
catechins
citicoline
coenzyme Q10 (CoQ10)
coffee fruit
copper
creatine monohydrate
d-alpha tocopherol
epigallocatechin gallate (EGCG)
fisetin
fish oil
flavonols
fructose
fruit and vegetable blend (proprietary)
glycerophosphocholine (GPC)
gooseberry
grape
greens blend (proprietary)
hesperetin
knotweed
krill oil
l-carnitine
l-carnosine
l-citrulline
l-glutathione
l-glycine
l-taurine
lentinula edodes mycelia
linoleic acid (LA)
liquid liver fractions
luteolin
mackerel
magnesium
maitake mushroom
malic acid
maltodextrin
maltose
manganese
maqui berry
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
moringa
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oleanolic acid
pantethine
pantothenic acid (vitamin B5)
phenolic acids
phosphatidylcholine
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
quercetin
quinoa
resveratrol
rhodiola
riboflavin (vitamin B2)
rosemary
sardines
selenium
black ginger
spinach
starch
stearic acid
strawberry
succinic acid
sulforaphane glucosinolate
thiamin (vitamin B1)
tocotrienols
trans-geranylgeraniol
trans-pterostilbene
tributyrin
turkey tail mushroom
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
vitamin B
vitamin B
vitamin D3
water
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β-nicotinamide mononucleotide (NMN)
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electrolytes blend (proprietary)
polyphenols
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thyroid substance
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Alpha polylactate
Apigenin
Alpha-Lipoic Acid
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adenosine triphosphate (ATP)
Animal protein
Beta-hydroxybutyrate
Beef liver
berry
Caffeic Acid
Centrophenoxine
Camellia sinensis
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Cocarboxylase
Capsinoids
Coenzyme A
Cardiolipin
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Creatine
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Products containing Lipids

We currently have no products on Vitabase that contain this ingredient.