Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Liver, particularly from beef and other animals, is sometimes used as a dietary supplement to support mitochondrial function. The rationale is based on its dense nutritional profile: liver is an exceptional source of vitamins B2 (riboflavin), B3 (niacin), B12, iron, and Coenzyme Q10 (CoQ10). These nutrients are critical cofactors in mitochondrial energy production pathways, including the electron transport chain and the Krebs cycle. For example, riboflavin and niacin are required for the formation of FAD and NAD+, essential for ATP production, while CoQ10 acts as an electron carrier in the mitochondrial membrane. Animal studies and some human data suggest that deficiencies in these nutrients can impair mitochondrial efficiency and that supplementation can improve mitochondrial function in deficient states.

However, while these mechanistic links are well established, direct clinical trials showing that liver supplementation improves mitochondrial function or related health outcomes in humans are limited. Most evidence is extrapolated from the known roles of its nutrients rather than from direct intervention studies using liver itself. Overall, using liver to support mitochondrial function is scientifically plausible because of its nutrient density, but the direct evidence base is moderate rather than strong.

More about Liver
More about Mitochondria

Other ingredients that support Mitochondria

7-Keto-DHEA
acetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
bovine liver
caffeine
catechins
citicoline
coenzyme Q10 (CoQ10)
coffee fruit
copper
creatine monohydrate
d-alpha tocopherol
epigallocatechin gallate (EGCG)
fisetin
fish oil
flavonols
fructose
fruit and vegetable blend (proprietary)
glycerophosphocholine (GPC)
gooseberry
grape
greens blend (proprietary)
hesperetin
knotweed
krill oil
l-carnitine
l-carnosine
l-citrulline
l-glutathione
l-glycine
l-taurine
lentinula edodes mycelia
linoleic acid (LA)
liquid liver fractions
luteolin
mackerel
magnesium
maitake mushroom
malic acid
maltodextrin
maltose
manganese
maqui berry
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
moringa
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oleanolic acid
pantethine
pantothenic acid (vitamin B5)
phenolic acids
phosphatidylcholine
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
quercetin
quinoa
resveratrol
rhodiola
riboflavin (vitamin B2)
rosemary
sardines
selenium
black ginger
spinach
starch
stearic acid
strawberry
succinic acid
sulforaphane glucosinolate
thiamin (vitamin B1)
tocotrienols
trans-geranylgeraniol
trans-pterostilbene
tributyrin
turkey tail mushroom
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
vitamin B
vitamin B
vitamin D3
water
watermelon
β-nicotinamide mononucleotide (NMN)
lingzhi
cistanche
ganoderma
electrolytes blend (proprietary)
polyphenols
trace minerals
fulvic acid
goji berry
herbal blend (proprietary)
algae
AMP-activated protein kinase (AMPK)
thyroid substance
ashitaba
1,3,7-Trimethylpurine-2,6-dione
5-Aminoimidazole-4-Carboxamide Ribonucleotide
Alpha polylactate
Apigenin
Alpha-Lipoic Acid
Ampelopsin
adenosine triphosphate (ATP)
Animal protein
Beta-hydroxybutyrate
Beef liver
berry
Caffeic Acid
Centrophenoxine
Camellia sinensis
Cardarine
Cocarboxylase
Capsinoids
Coenzyme A
Cardiolipin
Cyanidin
Capsiate
Chocolate
Creatine
C-Phycocyanin
Dihydrolipoic Acid
D-Ribose
Eriocitrin
Ergothioneine
glucose
Ketone Salts

Other body systems supported by Liver

Blood
Brain
Digestive System
Eyes
Glandular System
Hair
Hepatic System
Immune System
Intestinal System
Liver
Male Reproductive System
Mitochondria
Muscles
Nails
Spleen
Stomach

Products containing Liver

We currently have no products on Vitabase that contain this ingredient.