Marine fat, particularly from sources such as fish and krill, is rich in omega-3 polyunsaturated fatty acids (PUFAs), especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). There is considerable scientific evidence supporting the role of these compounds in supporting mitochondrial function. Omega-3 PUFAs are integral components of mitochondrial membranes, contributing to membrane fluidity and the function of embedded proteins involved in energy production. Several studies have demonstrated that omega-3 supplementation can enhance mitochondrial biogenesis, improve mitochondrial efficiency, and reduce oxidative stress within cells. For example, research published in journals such as Biochimica et Biophysica Acta and FASEB Journal has shown that EPA and DHA can upregulate genes involved in mitochondrial biogenesis (e.g., PGC-1α) and improve mitochondrial respiration in both animal models and humans. Additionally, omega-3 fatty acids exhibit anti-inflammatory properties, which can indirectly support mitochondrial health by reducing cellular stress. Overall, while more clinical trials are needed to clarify the specific effects in various populations, the current body of evidence provides a strong scientific rationale for the use of marine fats in supporting mitochondrial function.