Nannochloropsis is a genus of microalgae that has garnered attention for its high content of omega-3 fatty acids (particularly EPA), antioxidants such as carotenoids, and various vitamins. Its connection to mitochondrial support comes primarily from its nutrient profile. Mitochondria, known as the "powerhouses of the cell," rely on nutrients like polyunsaturated fatty acids and antioxidants to function optimally and to protect against oxidative damage.

Some in vitro and animal studies suggest that supplementation with omega-3 fatty acids and antioxidant compounds can enhance mitochondrial function, reduce oxidative stress, and support cellular energy production. Nannochloropsis has been shown in lab studies to be a potent source of these nutrients. However, there are no direct clinical studies demonstrating that Nannochloropsis supplementation improves mitochondrial function in humans. The evidence supporting its use is therefore extrapolated from its nutrient content and from broader studies on omega-3s and antioxidants.

In summary, the use of Nannochloropsis to support mitochondrial health is scientifically plausible due to its nutrient profile, but direct evidence is limited. Therefore, the evidence rating for this application is modest.