Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Peptides, particularly certain bioactive peptides, have garnered scientific interest for their role in mitochondrial health. Mitochondria are the energy-producing organelles in cells, and their function is critical to cellular health and energy metabolism. Scientific studies have shown that some peptides, such as mitochondrial-targeted peptides (e.g., SS-31, also known as Elamipretide), can directly interact with mitochondrial membranes, helping to preserve mitochondrial integrity, reduce oxidative stress, and improve mitochondrial function. These peptides have demonstrated protective effects in preclinical models of mitochondrial dysfunction, including models of neurodegenerative disease, cardiac injury, and muscle wasting.

While the field is still emerging and large-scale human clinical trials are limited, early-phase studies suggest that mitochondrial-targeted peptides may help maintain mitochondrial membrane potential, limit reactive oxygen species (ROS) production, and enhance ATP synthesis. Additionally, some naturally occurring peptides, such as those found in certain diets (e.g., whey protein-derived peptides), may indirectly support mitochondrial health by modulating inflammation and oxidative stress. However, the strongest evidence exists for synthetic, mitochondria-targeted peptides rather than dietary peptides in general.

In summary, there is a growing scientific basis—though not yet conclusive—for the use of specific peptides to support mitochondrial function, primarily in experimental settings. More research, especially in humans, is needed to establish definitive clinical benefits.

More about peptides (unspecified)
More about Mitochondria

Other ingredients that support Mitochondria

7-Keto-DHEA
acetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
bovine liver
caffeine
catechins
citicoline
coenzyme Q10 (CoQ10)
coffee fruit
copper
creatine monohydrate
d-alpha tocopherol
epigallocatechin gallate (EGCG)
fisetin
fish oil
flavonols
fructose
fruit and vegetable blend (proprietary)
glycerophosphocholine (GPC)
gooseberry
grape
greens blend (proprietary)
hesperetin
knotweed
krill oil
l-carnitine
l-carnosine
l-citrulline
l-glutathione
l-glycine
l-taurine
lentinula edodes mycelia
linoleic acid (LA)
liquid liver fractions
luteolin
mackerel
magnesium
maitake mushroom
malic acid
maltodextrin
maltose
manganese
maqui berry
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
moringa
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oleanolic acid
pantethine
pantothenic acid (vitamin B5)
phenolic acids
phosphatidylcholine
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
quercetin
quinoa
resveratrol
rhodiola
riboflavin (vitamin B2)
rosemary
sardines
selenium
black ginger
spinach
starch
stearic acid
strawberry
succinic acid
sulforaphane glucosinolate
thiamin (vitamin B1)
tocotrienols
trans-geranylgeraniol
trans-pterostilbene
tributyrin
turkey tail mushroom
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
vitamin B
vitamin B
vitamin D3
water
watermelon
β-nicotinamide mononucleotide (NMN)
lingzhi
cistanche
ganoderma
electrolytes blend (proprietary)
polyphenols
trace minerals
fulvic acid
goji berry
herbal blend (proprietary)
algae
AMP-activated protein kinase (AMPK)
thyroid substance
ashitaba
1,3,7-Trimethylpurine-2,6-dione
5-Aminoimidazole-4-Carboxamide Ribonucleotide
Alpha polylactate
Apigenin
Alpha-Lipoic Acid
Ampelopsin
adenosine triphosphate (ATP)
Animal protein
Beta-hydroxybutyrate
Beef liver
berry
Caffeic Acid
Centrophenoxine
Camellia sinensis
Cardarine
Cocarboxylase
Capsinoids
Coenzyme A
Cardiolipin
Cyanidin
Capsiate
Chocolate
Creatine
C-Phycocyanin
Dihydrolipoic Acid
D-Ribose
Eriocitrin
Ergothioneine
glucose
Ketone Salts

Other body systems supported by peptides (unspecified)

Brain
Gastrointestinal Tract
Glandular System
Hair
Immune System
Intestinal System
Joints
Mitochondria
Muscles
Nails
Skeletal System (Bones)
Skin

Products containing peptides (unspecified)

We currently have no products on Vitabase that contain this ingredient.