Evidence supporting the use of: Phenolic Acid
For the body system: Mitochondria
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Phenolic acids, a group of phytochemicals found in a variety of plant-based foods (such as coffee, fruits, and vegetables), have been studied for their antioxidant properties and potential benefits for mitochondrial function. Scientific evidence suggests that certain phenolic acids, including ferulic acid, caffeic acid, and gallic acid, can help protect mitochondria from oxidative stress. This is primarily due to their ability to scavenge free radicals and reduce mitochondrial damage, which is a key factor in cellular aging and various diseases.
Several in vitro and animal studies have demonstrated that phenolic acids can enhance mitochondrial biogenesis, stabilize mitochondrial membranes, and improve ATP production efficiency. For example, research in rodent models has shown that supplementation with phenolic acids may improve mitochondrial respiratory function and protect against mitochondrial dysfunction induced by toxins or age-related oxidative damage. Additionally, some studies have examined their role in neuroprotection, where improved mitochondrial function contributes to the protective effect.
However, human clinical data are limited, and most of the supporting evidence is preclinical. While the antioxidant and mitochondrial-supportive properties of phenolic acids are promising, more research is needed to fully validate their efficacy in humans for mitochondrial health. Thus, the scientific rating is moderate, reflecting promising but not yet definitive evidence for their use in supporting the mitochondrial body system.
Other ingredients that support Mitochondria
7-Keto-DHEAacetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
bovine liver
caffeine
catechins
citicoline
coenzyme Q10 (CoQ10)
coffee fruit
copper
creatine monohydrate
d-alpha tocopherol
epigallocatechin gallate (EGCG)
fisetin
fish oil
flavonols
fructose
fruit and vegetable blend (proprietary)
glycerophosphocholine (GPC)
gooseberry
grape
greens blend (proprietary)
hesperetin
knotweed
krill oil
l-carnitine
l-carnosine
l-citrulline
l-glutathione
l-glycine
l-taurine
lentinula edodes mycelia
linoleic acid (LA)
liquid liver fractions
luteolin
mackerel
magnesium
maitake mushroom
malic acid
maltodextrin
maltose
manganese
maqui berry
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
moringa
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oleanolic acid
pantethine
pantothenic acid (vitamin B5)
phenolic acids
phosphatidylcholine
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
quercetin
quinoa
resveratrol
rhodiola
riboflavin (vitamin B2)
rosemary
sardines
selenium
black ginger
spinach
starch
stearic acid
strawberry
succinic acid
sulforaphane glucosinolate
thiamin (vitamin B1)
tocotrienols
trans-geranylgeraniol
trans-pterostilbene
tributyrin
turkey tail mushroom
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
vitamin B
vitamin B
vitamin D3
water
watermelon
β-nicotinamide mononucleotide (NMN)
lingzhi
cistanche
ganoderma
electrolytes blend (proprietary)
polyphenols
trace minerals
fulvic acid
goji berry
herbal blend (proprietary)
algae
AMP-activated protein kinase (AMPK)
thyroid substance
ashitaba
1,3,7-Trimethylpurine-2,6-dione
5-Aminoimidazole-4-Carboxamide Ribonucleotide
Alpha polylactate
Apigenin
Alpha-Lipoic Acid
Ampelopsin
adenosine triphosphate (ATP)
Animal protein
Beta-hydroxybutyrate
Beef liver
berry
Caffeic Acid
Centrophenoxine
Camellia sinensis
Cardarine
Cocarboxylase
Capsinoids
Coenzyme A
Cardiolipin
Cyanidin
Capsiate
Chocolate
Creatine
C-Phycocyanin
Dihydrolipoic Acid
D-Ribose
Eriocitrin
Ergothioneine
glucose
Ketone Salts
Other body systems supported by Phenolic Acid
ArteriesBrain
Capillaries
Heart
Immune System
Intestinal System
Large Intestines (Colon)
Liver
Mitochondria
Skin