Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Phospholipids, particularly phosphatidylcholine and phosphatidylethanolamine, are integral components of mitochondrial membranes and play a critical role in maintaining mitochondrial structure and function. Scientific studies have demonstrated that phospholipids are essential for the optimal performance of mitochondrial respiratory enzymes and for the integrity of the mitochondrial inner membrane, where energy (ATP) production occurs. For example, alterations in mitochondrial phospholipid composition are associated with impaired mitochondrial function and increased oxidative stress, which are factors in various metabolic and neurodegenerative diseases.

Supplementation with specific phospholipids has been shown in some preclinical and limited clinical studies to support mitochondrial membrane repair and improve mitochondrial function. In particular, phosphatidylcholine supplementation has demonstrated benefits in animal models of mitochondrial dysfunction and some small human studies, such as in nonalcoholic fatty liver disease and certain neurodegenerative conditions, although large-scale clinical trials are lacking. Nonetheless, there is a plausible scientific rationale and some empirical evidence supporting the use of phospholipids for mitochondrial health, but the breadth and rigor of clinical evidence remain moderate.

It is important to note that research often focuses on specific types of phospholipids rather than "phospholipid (unspecified)" as a general category, and efficacy may vary depending on the specific compound and context. Overall, the scientific basis exists, but further research is needed to better define efficacy and clinical applications.

More about Phospholipid (unspecified)
More about Mitochondria

Other ingredients that support Mitochondria

7-Keto-DHEA
acetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
bovine liver
caffeine
catechins
citicoline
coenzyme Q10 (CoQ10)
coffee fruit
copper
creatine monohydrate
d-alpha tocopherol
epigallocatechin gallate (EGCG)
fisetin
fish oil
flavonols
fructose
fruit and vegetable blend (proprietary)
glycerophosphocholine (GPC)
gooseberry
grape
greens blend (proprietary)
hesperetin
knotweed
krill oil
l-carnitine
l-carnosine
l-citrulline
l-glutathione
l-glycine
l-taurine
lentinula edodes mycelia
linoleic acid (LA)
liquid liver fractions
luteolin
mackerel
magnesium
maitake mushroom
malic acid
maltodextrin
maltose
manganese
maqui berry
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
moringa
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oleanolic acid
pantethine
pantothenic acid (vitamin B5)
phenolic acids
phosphatidylcholine
pyridoxal-5-phosphate (P-5-P)
pyrroloquinoline disodium salt
quercetin
quinoa
resveratrol
rhodiola
riboflavin (vitamin B2)
rosemary
sardines
selenium
black ginger
spinach
starch
stearic acid
strawberry
succinic acid
sulforaphane glucosinolate
thiamin (vitamin B1)
tocotrienols
trans-geranylgeraniol
trans-pterostilbene
tributyrin
turkey tail mushroom
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
vitamin B
vitamin B
vitamin D3
water
watermelon
β-nicotinamide mononucleotide (NMN)
lingzhi
cistanche
ganoderma
electrolytes blend (proprietary)
polyphenols
trace minerals
fulvic acid
goji berry
herbal blend (proprietary)
algae
AMP-activated protein kinase (AMPK)
thyroid substance
ashitaba
1,3,7-Trimethylpurine-2,6-dione
5-Aminoimidazole-4-Carboxamide Ribonucleotide
Alpha polylactate
Apigenin
Alpha-Lipoic Acid
Ampelopsin
adenosine triphosphate (ATP)
Animal protein
Beta-hydroxybutyrate
Beef liver
berry
Caffeic Acid
Centrophenoxine
Camellia sinensis
Cardarine
Cocarboxylase
Capsinoids
Coenzyme A
Cardiolipin
Cyanidin
Capsiate
Chocolate
Creatine
C-Phycocyanin
Dihydrolipoic Acid
D-Ribose
Eriocitrin
Ergothioneine
glucose
Ketone Salts

Other body systems supported by Phospholipid (unspecified)

Brain
Circulatory System
Gastrointestinal Tract
Heart
Liver
Mitochondria
Nerves
Skin
Structural System

Products containing Phospholipid (unspecified)

We currently have no products on Vitabase that contain this ingredient.