Evidence supporting the use of: Polar Lipids (unspecified)
For the body system: Mitochondria

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Polar lipids, such as phospholipids and glycolipids, are fundamental components of biological membranes, including those of mitochondria. Scientific evidence supports the importance of these molecules for mitochondrial function, as they contribute to membrane fluidity, structure, and the formation of mitochondrial cristae, which are essential for oxidative phosphorylation and ATP production. Cardiolipin, a unique mitochondrial polar lipid, is particularly critical for the organization and activity of respiratory chain complexes. Studies have shown that alterations in polar lipid composition can impair mitochondrial energy metabolism and are implicated in various diseases and aging processes. Furthermore, supplementation with certain polar lipids (e.g., phosphatidylcholine, phosphatidylserine) has been explored for their potential to improve mitochondrial function or protect against mitochondrial dysfunction in cell and animal models. However, while there is a mechanistic and biochemical basis for the use of polar lipids to support mitochondrial health, direct clinical evidence in humans is still limited, and most research has focused on specific polar lipid classes rather than broad, unspecified mixtures. Therefore, the scientific rationale exists at the biochemical level, with moderate preclinical evidence, but more targeted clinical trials are needed to fully validate efficacy in human health and disease contexts.

More about Polar Lipids (unspecified)
More about Mitochondria

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l-carnitine
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l-glycine
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linoleic acid (LA)
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stearic acid
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Products containing Polar Lipids (unspecified)

We currently have no products on Vitabase that contain this ingredient.