Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Uridine monophosphate (UMP) has some scientific basis for its potential to support mitochondrial function, though the evidence is still emerging and not robust. UMP is a nucleotide involved in the synthesis of RNA and phospholipids, and plays a role in cellular metabolism. Preclinical studies, primarily in animal models, suggest that uridine, often in combination with choline and DHA, can enhance mitochondrial biogenesis and function, particularly in the brain. For example, uridine has been shown to increase the synthesis of phosphatidylcholine, a key component of mitochondrial membranes, and may enhance synaptic function and mitochondrial energetics. Some rodent studies indicate that uridine supplementation can improve mitochondrial function under stressful or neurodegenerative conditions, such as models of Alzheimer’s disease.

However, human clinical data directly linking UMP supplementation to improved mitochondrial health are limited. Most evidence comes from basic research or studies on neuroprotection and cognitive health, with mitochondrial support being a secondary or inferred outcome. There is no widespread traditional use of UMP specifically for mitochondria, as it is a relatively recent focus in nutritional neuroscience and biochemistry. In summary, while there is some preliminary scientific rationale for UMP's role in supporting mitochondrial structure and function, the current level of evidence is modest and primarily limited to animal studies and mechanistic insights.

More about Uridine monophosphate
More about Mitochondria

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l-carnitine
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l-citrulline
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linoleic acid (LA)
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niacin (vitamin B3)
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riboflavin (vitamin B2)
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Other body systems supported by Uridine monophosphate

Brain
Mitochondria
Nerves
Specific Neurotransmitters

Products containing Uridine monophosphate

We currently have no products on Vitabase that contain this ingredient.