Evidence supporting the use of: Vitamin E (Gamma Tocotrienol)
For the body system: Mitochondria

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Gamma Tocotrienol is one of the four tocotrienol isomers in the Vitamin E family. Its use to support mitochondrial function has some grounding in scientific research, though the evidence is not robust and primarily comes from preclinical studies. Tocotrienols, including gamma tocotrienol, are potent antioxidants, and mitochondria are particularly susceptible to oxidative stress due to their role in cellular energy production. Several in vitro and animal studies suggest that gamma tocotrienol can help protect mitochondria from oxidative damage, improve mitochondrial membrane potential, and potentially promote mitochondrial biogenesis. For example, research has demonstrated that tocotrienols reduce reactive oxygen species (ROS) generation and preserve mitochondrial function in models of neurodegenerative diseases and metabolic syndrome.

However, direct clinical evidence in humans is sparse. Most of the supporting data are preclinical, and while they are promising, they do not yet constitute strong evidence for mitochondrial support in humans. Additionally, tocotrienols as a group are more commonly studied than gamma tocotrienol alone, so the specific effects of the gamma isomer are not fully differentiated. Overall, while there is some scientific rationale for using gamma tocotrienol to support mitochondrial health, the level of evidence is currently limited, justifying a moderate rating.

More about Vitamin E (Gamma Tocotrienol)
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Products containing Vitamin E (Gamma Tocotrienol)

We currently have no products on Vitabase that contain this ingredient.