Evidence supporting the use of: Gambir
For the body system: Mucus Membranes
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Gambir (Uncaria gambir), also known as cat's claw or gambier, is a traditional herbal remedy derived from the leaves and young shoots of the Uncaria plant. Its primary use in traditional medicine, particularly in Southeast Asia and traditional Chinese medicine, has been as an astringent and for supporting mucous membrane health. Historically, gambir has been chewed with betel nut or used in extracts to soothe sore throats, treat diarrhea, and manage oral and throat inflammations—conditions closely linked with mucous membrane integrity and function.
The traditional rationale centers on its high content of tannins, which are known for their astringent (tissue-tightening and drying) effects. These properties were believed to help reduce excess mucus, soothe irritated tissues, and support the healing of minor wounds in the mouth and throat. However, while there are historical records and ethnobotanical reports attesting to these uses, there is a lack of robust modern scientific studies directly validating gambir's efficacy for mucous membrane support. A small number of laboratory studies suggest antimicrobial and anti-inflammatory properties, but clinical trials are lacking.
In summary, the use of gambir for mucous membranes is primarily based on longstanding traditional practices, with limited scientific investigation. Therefore, the evidence rating is moderate for traditional use but low for scientific validation.
Other ingredients that support Mucus Membranes
AcaciaAcemannan
Adenophora
Agastache
Agrimony
Akkermansia muciniphila
Alchornea
Allicin
Aloe vera
Arisaema
arrowroot
asarabacca
Asarum heterotropoides
Asarum sieboldii
aster root
Baccharis dracunculifolia
bael
bai ji
Baikal Skullcap
balloon flower
balsam
Barleria
barley
basil
bayberry
bee products
bee propolis
Belamcanda
benzoin
beta-carotene
bethroot
Bidens pilosa
bilberry
bioflavonoids
bird\'s nest
bistort
black seed
blackberry
Bletilla
boneset
borage
Boswellia
Boswellic Acid
Bougainvillea
broccoli
Bryonia
butterbur
cajuput
Calendula
cantaloupe
capsicum
cardamom
carotene (unspecified)
carvacrol
catechu
cayenne pepper
Centipeda
ceramides
chamomile
Chekiang Fritillary
chickweed
Chondrus
cineole
Cistus
Citrus
citrus bioflavonoids
clove
cod liver oil
Collinsonia
colloidal silver
colostrum
coltsfoot
Coptis chinensis
cornflower
cowslip
cranesbill
cubeb
dandelion
devil\'s club
Echinacea
Elder
elecampane
elephant\'s head
ellagitannin
English elm
English horsemint
eucalyptus
Eucheuma
European Elder
European field elm
European five-finger grass
Eyebright
fireweed
flavanones
flavonones
fleabane
fritillaria
fritillary
fruit
fruit and vegetable blend (proprietary)
Gambir
Gigartina
Glechoma hederacea
Gleditsia
Glehnia littoralis
glehnia root
Glycosaminoglycans
Glycyrrhetinic acid
Glycyrrhizin
goldenseal
goldthread
Grindelia
Guaco
Gumweed
heal-all
Heartsease
Hedychium spicatum
Heliopsis
herbal blend (proprietary)
honey
honey loquat syrup
horehound
horseradish
Houttuynia
Indian ipecac
Jaboticaba
Kefiran
L-cysteine
L-threonine
labrador tea
Lactobacillus crispatus
Lactobacillus jensenii
Lactobacillus kefiranofaciens
Lactobacillus salivarius
Lactoferrin
Lactoperoxidase
Large-leaved linden
lemon
Leptospermum scoparium
licorice root
Ligusticum
linden
lobelia
Lomatium
loquat
luffa
lungwort
lysozyme
Mahonia
Maidenhair Fern
malabar nut
mallow
Malva sylvestris
marigold
Marshmallow
Matico
Meadowsweet
Menthol oil
Methylmethionine sulfonium chloride (vitamin U)
Mimosa
Mineral ascorbate
Mint
mixed carotenoids
Monardella odoratissima
Moss
Mountain horopito
Mucilage
Mucin
Mugwort
Mullein
Myrrh
N-acetyl-cysteine (NAC)
N-acetyl-glucosamine
N-acetylneuraminic acid
Nasturtium
Nettle
Niacin (vitamin B3)
Nigella seed
okra
olive
omega-7 fatty acids
onion
Onosma bracteatum
Ophiopogon
ophiopogon root
oregon grape
Osha
Panthenol
pear
Pelargonium
Pellitory
perilla
Persimmon
Phenylpropanoids
Pinellia ternata
Plantago
plantain
Platycodon
platycodon root
Plectranthus amboinicus
Polygonatum
Portulaca
Potentilla
prebiotic blend (proprietary)
probiotics
Propolis
Pseudostellaria
Pulsatilla
purple loosestrife
raspberry
ravinsara
red root
red soapwort
Rhus glabra
riboflavin (vitamin B2)
Rosa californica
rose
rose oil
rosmarinic acid
Rumex acetosa
Sabadilla
sage
Sambucus nigra
Sanguisorba
Sanicle
Serrapeptase
Sidalcea glaucescens
Slippery Elm
slippery elm bark
Speedwell
Spilanthes
Stemona
Stillingia
Storax
Streptococcus salivarius
Sulfated polysaccharide
Sundew
Tannins
Terminalia
Teucrium marum
Thuja
thyme
Thymol
Toothache Plant
Tragacanth
Tremella
Tylophora
Ulmus
Umckalin
Umckaloabo
Vasicine
Vasicinol
Vasicinone
Veronica
Viola
vitamin A
vitamin C
vitamin E
White Dead Nettle Flower
White oak
Yarrow
Yellow root
Yerba Mansa
Yerba santa
zanthoxylum
zhejiang fritillary
Zinc
Other body systems supported by Gambir
Digestive SystemGastrointestinal Tract
Gums
Mucus Membranes
Skin
Teeth
