Gigartina, a genus of red seaweed, has traditionally been used in various cultures for its mucilaginous properties, which suggest a potential benefit for supporting mucus membranes. These seaweeds are rich in sulfated polysaccharides, such as carrageenans, which form gels and have been utilized in folk remedies to soothe irritated tissues, particularly in the respiratory and digestive tracts. Traditional use includes preparations as teas, syrups, or poultices for coughs, sore throats, and gastrointestinal discomfort, all of which involve the mucus membranes. However, while these uses are well documented in ethnobotanical literature, there is limited scientific evidence specifically validating Gigartina’s effectiveness in supporting mucus membranes in humans. Most scientific studies on Gigartina focus on its antiviral, immunomodulatory, or anti-inflammatory effects, with few directly examining its impact on mucus membrane health. Thus, the rationale for its use in supporting mucus membranes is primarily based on tradition and its known mucilage content, rather than robust clinical trials or mechanistic studies.