Gingerol, the primary bioactive compound in ginger (Zingiber officinale), has been studied for its effects on the mucus membranes, particularly within the respiratory and gastrointestinal tracts. Scientific evidence suggests that gingerol exhibits anti-inflammatory and antioxidant properties, which may help in protecting and soothing mucus membranes. Research indicates that ginger extracts can reduce inflammation in the airways, potentially benefiting conditions such as sore throat and cough, which are associated with irritation of the respiratory mucus membranes (Grzanna et al., 2005). Additionally, gingerol is known to stimulate saliva and bile production, which may further protect and hydrate mucosal linings in the mouth and digestive tract.

Clinical studies are limited, but some in vitro and animal models support gingerol’s role in mucosal protection, likely due to its ability to reduce oxidative stress and inhibit pro-inflammatory cytokines. Traditional medicine systems, such as Ayurveda and Traditional Chinese Medicine, have also used ginger for respiratory and digestive complaints, often attributing its effects to its warming properties and ability to disperse phlegm. However, while the preclinical evidence is promising, more robust human trials are needed to confirm these effects and establish standardized dosing for the support of mucus membranes.