Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Horehound (Marrubium vulgare) has a long history of use in traditional herbal medicine for supporting the respiratory tract and mucus membranes. Historically, horehound has been used as an ingredient in cough syrups, lozenges, and teas intended to soothe sore throats, ease coughs, and promote expectoration. Its traditional use dates back to ancient Greek and Roman times, where it was recommended by herbalists such as Dioscorides and Galen for respiratory complaints.

The traditional rationale for using horehound is based on its content of bitter compounds (notably marrubiin), which are thought to stimulate the secretion of mucus and help clear phlegm from the airways. This expectorant effect is central to its reputation as a remedy for coughs and bronchial irritation. Various pharmacopeias, especially in Europe, have recognized horehound for these purposes.

Scientific evidence supporting these uses is limited, but some laboratory studies suggest that marrubiin may have mild expectorant and antitussive properties. However, well-controlled clinical trials in humans are lacking, and therefore, the evidence does not rise to the level of strong scientific validation. The rating of 3 reflects a substantial traditional basis with modest preliminary scientific support, but not enough rigorous clinical data to recommend it based solely on science.

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