Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Kefiran is a polysaccharide produced by certain lactic acid bacteria found in kefir grains. Scientific studies investigating kefiran’s effects on mucus membranes are limited but suggest some potential benefits. Kefiran has demonstrated immunomodulatory and anti-inflammatory properties in animal models. A few in vivo studies have shown that kefiran may increase mucin production and enhance the integrity of the intestinal mucosal barrier. For example, animal studies report that kefiran administration can increase the thickness and quality of the intestinal mucus layer, potentially protecting against gut inflammation and infection (Maeda et al., 2004; Vinderola et al., 2006). Additionally, kefiran appears to encourage the growth of beneficial gut bacteria, which are essential for maintaining healthy mucus membranes in the gastrointestinal tract.

However, most of the evidence comes from preclinical studies, primarily in rodents, with very limited human data available. There is not yet robust clinical evidence to support kefiran’s use specifically for mucus membrane health in humans. While its traditional use as part of kefir may contribute to mucosal health, the direct application of isolated kefiran for this purpose is still under investigation. Overall, while there are scientific indications of benefit, the strength of evidence is currently moderate to low (rated 2/5), and further clinical studies are needed to validate its efficacy in humans.

More about Kefiran
More about Mucus Membranes

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Cineole
Cornflower
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Other body systems supported by Kefiran

Digestive System
Gastrointestinal Tract
Immune System
Intestinal System
Large Intestines (Colon)
Mucus Membranes

Products containing Kefiran

We currently have no products on Vitabase that contain this ingredient.