Evidence supporting the use of: Lactobacillus kefiranofaciens
For the body system: Mucus Membranes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactobacillus kefiranofaciens is a probiotic bacterium commonly found in traditional kefir grains. There is emerging scientific evidence suggesting that this microorganism may help support the health of mucus membranes, particularly those in the gastrointestinal tract. Studies (mainly in vitro and in animal models) have shown that L. kefiranofaciens can enhance the production of mucins, the primary components of the protective mucus layer lining the gut. This enhanced mucin production contributes to maintaining the integrity of the intestinal barrier, protecting against pathogen invasion, and modulating local immune responses.

For example, research published in peer-reviewed journals has demonstrated that kefiran, an exopolysaccharide produced by L. kefiranofaciens, can stimulate goblet cells to secrete more mucus and may influence the expression of tight junction proteins, further supporting the mucus barrier. Additionally, animal studies indicate that supplementation with L. kefiranofaciens can reduce inflammation and promote mucosal healing in models of colitis.

However, while these results are promising, direct evidence from well-designed human clinical trials is limited. Most of the current support comes from laboratory and animal data, with a few small-scale human studies or extrapolations from broader kefir research. Thus, the use of L. kefiranofaciens to support mucus membranes is scientifically plausible and partially validated, but further research in humans is needed to fully substantiate its efficacy.

More about Lactobacillus kefiranofaciens
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Products containing Lactobacillus kefiranofaciens

We currently have no products on Vitabase that contain this ingredient.