Evidence supporting the use of: Licorice (various)
For the body system: Mucus Membranes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Licorice (Glycyrrhiza glabra) has a long history of traditional use for soothing and protecting mucus membranes, particularly in the respiratory and digestive tracts. Modern scientific research offers some validation for these uses. The primary active components in licorice, such as glycyrrhizin and flavonoids, exhibit anti-inflammatory, demulcent, and mucoprotective properties. Several in vitro and animal studies have demonstrated that licorice extracts can enhance mucus secretion, promote the repair of epithelial tissues, and inhibit the adhesion of certain pathogens to mucosal surfaces.

Clinical studies support the use of deglycyrrhizinated licorice (DGL) in the management of gastric ulcers and other gastrointestinal complaints, likely due to its ability to increase mucin production and protect the stomach lining. There is also evidence suggesting that licorice preparations can soothe sore throats and aid in the relief of upper respiratory tract irritation by forming a protective film over inflamed tissues.

However, while preclinical and limited clinical data are promising, comprehensive human trials are still relatively sparse. Safety concerns also exist with prolonged or high-dose use due to glycyrrhizin’s potential to cause hypertension and hypokalemia. Overall, licorice's use to support mucus membranes is justified by both tradition and a moderate level of scientific evidence, but should be approached with attention to dosing and duration.

More about Licorice (various)
More about Mucus Membranes

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Products containing Licorice (various)

We currently have no products on Vitabase that contain this ingredient.