Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Niacin (vitamin B3) has scientific validation for its role in supporting the health of mucus membranes. Niacin is an essential water-soluble vitamin that is fundamental to cellular metabolism and the maintenance of epithelial tissues, which include the mucus membranes lining the digestive tract, respiratory system, and other parts of the body. The most direct evidence comes from the consequences of niacin deficiency: pellagra. Pellagra is characterized by the "three Ds"—dermatitis, diarrhea, and dementia—with the dermatitis and diarrhea components closely linked to damage and inflammation of epithelial and mucosal tissues. Specifically, pellagra can cause glossitis (inflammation of the tongue), stomatitis (inflammation of the mouth), and gastrointestinal tract inflammation, all of which are associated with mucus membranes. When niacin levels are restored, these symptoms typically resolve, demonstrating the vitamin’s importance in maintaining mucosal integrity.

However, while severe deficiency is clearly harmful to mucus membranes, there is limited evidence that niacin supplementation above recommended dietary intakes provides additional benefit to mucus membrane health in otherwise healthy individuals. Most scientific literature supports niacin's essentiality for baseline maintenance rather than enhanced support or therapeutic use for mucus membranes. Thus, the evidence supports a moderate score of 3: it is essential and deficiency causes clear mucus membrane pathology, but there is not strong evidence for benefit beyond deficiency prevention.

More about Niacin (vitamin B3)
More about Mucus Membranes

Other ingredients that support Mucus Membranes

Other body systems supported by Niacin (vitamin B3)

Products containing Niacin (vitamin B3)

Integrative Therapeutics Active B-Complex
Metagenics AdvaClear
Metagenics AdvaClear
Douglas Laboratories B-Complex
Pure Encapsulations B-Complex Plus
Pure Encapsulations B-Complex Plus
Designs For Health B-Supreme
Pure Encapsulations B6 Complex
Pure Encapsulations B6 Complex
Thorne Basic B Complex
Metagenics Bone Builder Active
Vitabase Cholesterol Support
Metagenics Clear Change Daily Essentials
Integrative Therapeutics Detoxication Factors
Integrative Therapeutics Detoxication Factors
Designs For Health DFH Complete Multi™
Designs For Health DFH Complete Multi™ with Copper
Designs For Health DFH Complete Multi™ with Copper & Iron
Pure Encapsulations Energize Plus™ Pure Pack
Metagenics Fem Prenatal®
Integrative Therapeutics Flush-Free Niacin
Metagenics Glutagenics
Metagenics Glycogenics
Vitabase Hair, Skin & Nails Formula
Pure Encapsulations Hair/Skin/Nails Ultra
Metagenics ImmuCore
Metagenics Immune Defense Pack
Metagenics Ketogenic Shake Chocolate
Metagenics Ketogenic Shake Vanilla
Klean Athlete Klean Multivitamin ™
Vitabase Life's Essentials Plus
Designs For Health Liposomal B Supreme
Metagenics Lipotain®
Thorne MediClear Plus
Thorne Men's Multi 50+
Designs For Health Metabolic Synergy™
Designs For Health Metabolic Synergy™
Metagenics MetaKids Nutrition Powder Chocolate
Metagenics MetaKids Nutrition Powder Vanilla
Pure Encapsulations Multi t/d
Pure Encapsulations Multi t/d
Thorne Multi-Vitamin Elite NSF
Thorne Multi-Vitamin Elite NSF
Metagenics Multigenics®
Metagenics Multigenics Intensive Care
Metagenics Multigenics Intensive Care without Iron
Metagenics Multigenics without Iron
Integrative Therapeutics Multiplex-1 No-Iron
Pure Encapsulations NeuroMood Pure Pack
Pure Encapsulations Niacinamide
Pure Encapsulations Niacitol® 500 mg
Pure Encapsulations Niacitol® (no-flush niacin) 650 mg
Douglas Laboratories Niatab ™ 500
Metagenics Niatain®
Pure Encapsulations Nutrient 950®
Pure Encapsulations Nutrient 950®
Pure Encapsulations Nutrient 950®
Pure Encapsulations Nutrient 950® A without Copper & Iron
Pure Encapsulations Nutrient 950® with NAC
Pure Encapsulations Nutrient 950® with Vitamin K
Pure Encapsulations Nutrient 950® without Copper, Iron & Iodine
Pure Encapsulations Nutrient 950® without Iron
Pure Encapsulations Nutrient 950® without Iron
Integrative Therapeutics Nutrivitamin No-Iron
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Integrative Therapeutics Osteoprime Forte
Designs For Health PaleoMeal®
Designs For Health PaleoMeal®
Integrative Therapeutics Physicians Elemental Diet Dextrose Free
Integrative Therapeutics Physician's Elemental Diet
Integrative Therapeutics Physician's Elemental Diet
Integrative Therapeutics Physicians Elemental Diet Kit
Metagenics PhytoMulti™ Multivitamin
Metagenics PhytoMulti With Iron
Metagenics PhytoMulti Without Iron
Metagenics PhytoMultivitamin
Metagenics PlusOne® Daily Prenatal Packs
Pure Encapsulations Polyphenol Nutrients
Pure Encapsulations Polyphenol Nutrients
Pure Encapsulations PreNatal Nutrients
Pure Encapsulations PreNatal Nutrients
Designs For Health Primal Multi™
Integrative Therapeutics ProThrivers Multivitamin
Pure Encapsulations PureGenomics® B-Complex
Pure Encapsulations PureGenomics® Multivitamin
Pure Encapsulations PureGenomics® UltraMultivitamin
Pure Encapsulations PureLean® Protein
Designs For Health Twice Daily Essential Packets
Designs For Health Twice Daily Multi™
Designs For Health Twice Daily Multi™
Designs For Health Twice Daily Multi™
Douglas Laboratories Ultra B-Complex
Pure Encapsulations Ultra B-Complex with PQQ
Metagenics Ultra Glucose Control® Chocolate
Metagenics Ultra Glucose Control Chocolate
Metagenics Ultra Glucose Control Vanilla
Metagenics Ultra Glucose Control Vanilla
Metagenics Ultra Potent-C 1000
Metagenics Ultra Potent-C 500
Metagenics Ultra Potent-C Chewable
Metagenics Ultra Potent-C Powder
Douglas Laboratories Ultra Preventive
Douglas Laboratories Ultra Preventive
Douglas Laboratories Ultra Preventive 50+ -EZ Swallow
Douglas Laboratories Ultra Preventive ®-EZ Swallow
Douglas Laboratories ULTRA PREVENTIVE® III W/COPPER
Douglas Laboratories Ultra Preventive ® Kids Grape Flavor
Douglas Laboratories Ultra Preventive ® Kids Orange Flavor
Douglas Laboratories Ultra Preventive® X
Pure Encapsulations Ultra Pure Pack
Metagenics UltraGI Replenish® Chocolate
Metagenics UltraGI Replenish Chocolate
Metagenics UltraGI Replenish Vanilla
Metagenics UltraGI Replenish Vanilla
Metagenics UltraInflamX Plus 360°® Chocolate/Orange
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Orange
Metagenics UltraInflamX Plus 360° Original Spice
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraMeal Advanced Protein® Dutch Chocolate
Metagenics UltraMeal Advanced Protein French Vanilla
Metagenics UltraMeal Advanced Protein Plain
Metagenics UltraMeal Cardio 360°® Pea/Rice Chocolate
Metagenics UltraMeal Cardio 360° Pea/Rice Vanilla
Metagenics UltraMeal® Daily Support Dutch Chocolate
Metagenics UltraMeal Daily Support Mixed Berry
Metagenics UltraMeal Rice Vanilla
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Pure Encapsulations VisionPro Nutrients
Metagenics Wellness Essentials Active Daily Packs
Metagenics Wellness Essentials Brain Health Daily Packs
Metagenics Wellness Essentials® Daily Packs
Metagenics Wellness Essentials Healthy Balance Daily Packs
Metagenics Wellness Essentials Men's Vitality Daily Packs
Metagenics Wellness Essentials Women's Daily Packs
Metagenics Wellness Essentials Women's Prime Daily Packs
Thorne Women's Multi 50+
Pure Encapsulations Women's Nutrients
Pure Encapsulations Women's Nutrients
Designs For Health Women's Twice Daily Essential Packets