Sea Buckthorn Oil (Hippophae rhamnoides) has a long history of use in traditional medicine for supporting the health of mucus membranes, particularly in the respiratory, digestive, and genitourinary tracts. In recent decades, scientific research has begun to validate these traditional uses. Sea Buckthorn Oil is rich in omega-7 fatty acids (notably palmitoleic acid), as well as vitamin E, carotenoids, and phytosterols. These compounds are thought to contribute to its ability to support and maintain the integrity of epithelial tissues, including mucus membranes.

Several clinical and preclinical studies have investigated these effects. For example, randomized controlled trials have shown that oral supplementation with sea buckthorn oil can improve symptoms of dry eye syndrome (a condition involving the mucus membranes of the eye), likely by influencing the lipid content and stability of the tear film. Other studies have suggested benefits for atrophic vaginitis and dry mouth, both of which involve mucosal tissues. Proposed mechanisms include anti-inflammatory effects, enhancement of mucosal barrier function, and improved tissue hydration.

While the body of evidence is not yet comprehensive and more large-scale human trials are needed, the available data provide moderate support for the use of sea buckthorn oil in maintaining and supporting mucus membrane health. Thus, scientific validation is emerging, especially for specific conditions related to mucosal dryness.