Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Umckalin and the Mucus Membranes Body System

Umckalin is a coumarin compound found in the roots of Pelargonium sidoides, a plant traditionally used in South African medicine. Extracts from this plant, commonly referred to as Umckaloabo, are standardized and marketed for the treatment of acute bronchitis, sinusitis, and other respiratory tract infections, which involve the mucus membranes of the respiratory system.

The scientific validation for Umckalin (and Pelargonium sidoides extracts in general) comes from several clinical studies and reviews. These studies demonstrate that the extracts can reduce the duration and severity of symptoms in acute bronchitis and other upper respiratory infections. The proposed mechanisms include antimicrobial, antiviral, and immunomodulatory effects, along with an increase in mucociliary clearance, which supports the function of mucus membranes in the airways.

However, it's important to note that most research evaluates whole root extracts rather than isolated Umckalin. While Umckalin is considered one of the marker compounds, the evidence typically attributes the benefits to the combined phytochemical profile of the extract. Systematic reviews and meta-analyses (e.g., Cochrane Reviews) generally conclude there is moderate evidence for efficacy and safety of Pelargonium sidoides extracts in treating acute respiratory tract infections.

In summary, the use of Umckalin-containing extracts to support mucus membrane health in the respiratory tract is scientifically grounded, but the evidence is modest and primarily applies to the whole extract rather than the isolated compound.

More about Umckalin
More about Mucus Membranes

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Other body systems supported by Umckalin

Bronchials
Eustachian Tubes
Immune System
Lungs
Mucus Membranes
Respiratory System
Sinuses

Products containing Umckalin

We currently have no products on Vitabase that contain this ingredient.