Evidence supporting the use of: Cannabinoids
For the health condition: Muscle Tone (lack of)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cannabinoids, particularly those derived from the cannabis plant such as cannabidiol (CBD) and tetrahydrocannabinol (THC), have been investigated for their effects on muscle tone, especially in the context of neurological disorders like multiple sclerosis (MS) that are characterized by spasticity or abnormal muscle tone. The most substantial evidence comes from clinical studies focusing on the management of spasticity, a condition involving increased muscle tone, rather than hypotonia (lack of muscle tone). The oromucosal spray Sativex (nabiximols), which contains a combination of THC and CBD, has been approved in several countries for the treatment of MS-related spasticity. Randomized controlled trials have demonstrated that nabiximols can reduce spasticity scores in some patients, though the effect size is generally modest and not all patients respond. There is limited evidence to suggest that cannabinoids improve muscle tone in cases where tone is lacking (hypotonia). Most research and clinical applications focus on reducing excessive muscle tone rather than increasing it. Preclinical studies and anecdotal reports suggest a potential role for cannabinoids in modulating the endocannabinoid system, which is involved in motor control, but conclusive evidence for treating hypotonia is lacking. Thus, while there is some scientific validation for the use of cannabinoids in abnormal muscle tone (spasticity), their use for specifically increasing muscle tone (addressing hypotonia) is not well supported.

More about Cannabinoids
More about Muscle Tone (lack of)

Products containing Cannabinoids

We currently have no products on Vitabase that contain this ingredient.