Evidence supporting the use of: Conjugated linoleic acid (CLA)
For the health condition: Muscle Tone (lack of)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Conjugated linoleic acid (CLA) is a fatty acid found naturally in meat and dairy products, and it has been marketed as a dietary supplement for improving body composition, particularly by reducing body fat and supporting muscle tone. The scientific rationale is based on animal studies and some small-scale human trials suggesting that CLA may reduce adipose tissue and potentially preserve or slightly increase lean muscle mass during weight loss. However, the quality and consistency of evidence in humans are limited.
A handful of randomized controlled trials in humans have shown modest effects of CLA supplementation on fat loss, but the impact on actual muscle mass or "muscle tone" is minimal and often not statistically significant. Meta-analyses suggest that while CLA might contribute to a small reduction in body fat, its effect on increasing or maintaining muscle mass is weak. Furthermore, the clinical relevance of these changes is questionable, as the improvements in body composition are typically minor.
Current scientific consensus does not robustly support the use of CLA for enhancing muscle tone, and safety concerns (such as potential adverse effects on lipid profiles and insulin sensitivity) have been raised with long-term supplementation. In summary, while there is some scientific investigation into CLA for body composition, the strength of evidence supporting its effectiveness for improving muscle tone is low.
More about conjugated linoleic acid (CLA)
More about Muscle Tone (lack of)
Other ingredients used for Muscle Tone (lack of)
adenosine 5-triphosphate disodium (ATP)alpha-ketoglutarate (AKG)
amino acids
ashwagandha
astaxanthin
beet
branched-chain amino acids
calcium
caterpillar mushroom
cissus quadrangularis
coenzyme Q10 (CoQ10)
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
fish protein
l-isoleucine
l-arginine
l-carnitine
l-citrulline
l-leucine
l-valine
maca
magnesium
ornithine alpha-ketoglutarate
phytocannabinoids
potassium
sardines
black ginger
tongkat ali
Urolithin A
vitamin D
whey protein
atractylodes
cistanche
electrolytes blend (proprietary)
camphor oil
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
Aralia
Arginine Alpha Ketoglutarate
Antler
Arginine Creatine
Alpha-ketoisocaproic acid
Algal protein
Alpha hydroxyisocaproic acid
Animal protein
Beef Protein
Beef
Beef liver
Bovine Protein
beta-lactoglobulin
Banyan
Ba Ji Tian
BCAA
Casein
Chinese Silkvine
Chinese Mountain Ant
Cyathula
Chuchuhuasi
Creatine
Chicken
Deer Velvet
Eurycomanone
Egg
Eurycoma Longifolia
Ecdysteroids
Ecdysterone
Egg protein
Fish
Ginsenosides
Isoleucine
Milk Protein
Quinoa Protein
salt
Other health conditions supported by conjugated linoleic acid (CLA)
ArthritisAthletic and Exercise Aids
Body Building
Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Fat Metabolism (poor)
Fatty Liver Disease
Inflammation
Metabolic Syndrome
Muscle Tone (lack of)
Osteoporosis
Triglycerides (high)
Weight Loss
Products containing conjugated linoleic acid (CLA)
Designs For Health
CLA
Pure Encapsulations
CLA 1000 mg
Pure Encapsulations
CLA 1000 mg
Douglas Laboratories
CLA (Conjugated Linoleic Acid)
Designs For Health
Plant Protein Meal
Designs For Health
Plant Protein Meal Plus
Designs For Health
Plant Protein Meal
Vitabase
Super Fat Burner