Evidence supporting the use of: Creatine glutamine
For the health condition: Muscle Tone (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Creatine and glutamine are both well-studied supplements in the context of muscle health, though their roles differ. Creatine is supported by robust scientific evidence for improving muscle strength, power, and mass, particularly in conjunction with resistance training. It acts by replenishing adenosine triphosphate (ATP) stores in muscle cells, which supports energy production during high-intensity, short-duration activities. Numerous randomized controlled trials and meta-analyses have shown that creatine supplementation increases muscle mass and enhances muscle function, making it a validated intervention for improving muscle tone, especially in populations with muscle weakness or sarcopenia.

Glutamine, on the other hand, is an amino acid involved in immune function and gut health. It is often marketed for muscle recovery, but scientific evidence supporting its effectiveness in directly increasing muscle tone or mass is limited compared to creatine. Some studies have investigated glutamine’s role in reducing muscle soreness or aiding recovery, but results are inconsistent.

Combining creatine and glutamine is sometimes promoted for overall muscle support. However, the evidence base for improved muscle tone primarily applies to creatine. In summary, creatine (not glutamine) is scientifically validated for supporting muscle tone, with a strong evidence base (rated 4/5), while glutamine’s role is much less clear.

More about Creatine glutamine
More about Muscle Tone (lack of)

Other health conditions supported by Creatine glutamine

Athletic and Exercise Aids
Fatigue
Muscle Tone (lack of)
Muscular Dystrophy
Wasting

Products containing Creatine glutamine

We currently have no products on Vitabase that contain this ingredient.