Evidence supporting the use of: L-carnitine
For the health condition: Muscle Tone (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-carnitine is a naturally occurring compound involved in the transport of long-chain fatty acids into the mitochondria for energy production, particularly in muscle cells. Its role in energy metabolism has led to interest in its potential to improve muscle function and tone, especially in individuals with deficiency or certain medical conditions. Several studies have examined L-carnitine supplementation in populations such as the elderly, individuals with chronic diseases (e.g., chronic kidney disease, heart failure), or those suffering from muscle wasting (sarcopenia). Some evidence suggests that L-carnitine can reduce muscle fatigue, improve exercise recovery, and possibly enhance muscle mass or strength, especially in carnitine-deficient states. However, in healthy individuals, the benefits for muscle tone or strength are less clear and often modest at best. The most consistent findings relate to improved muscle function in clinical populations rather than enhancement of muscle tone per se in healthy adults. Reviews and meta-analyses indicate that while L-carnitine has some effects on muscle recovery and fatigue, robust increases in muscle tone are not well established. Therefore, while there is some scientific support—mainly for specific populations—the overall evidence for using L-carnitine to enhance or treat lack of muscle tone in the general population is limited.

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