Evidence supporting the use of: L-valine
For the health condition: Muscle Tone (lack of)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
L-valine is an essential branched-chain amino acid (BCAA) that, along with leucine and isoleucine, plays a role in muscle metabolism and maintenance. Its use to support muscle tone, especially in cases of muscle wasting or lack of muscle tone, is primarily based on its biochemical role in protein synthesis and muscle repair. Some clinical studies have shown that BCAA supplementation — including L-valine — may help reduce muscle breakdown and support muscle maintenance in specific populations, such as athletes during intense training or individuals with muscle wasting due to illness. However, the evidence is not robust or specific to L-valine alone; most research examines BCAAs as a group, and the contribution of valine compared to leucine (the most studied BCAA) is less clear. The clinical benefit of supplementation in healthy individuals or those with mild muscle tone issues is not well established, and more research is needed to determine efficacy and optimal dosing. Thus, while there is a scientific rationale and some clinical evidence supporting its use for muscle tone, the strength of evidence is modest and primarily extrapolated from studies on BCAAs generally rather than L-valine specifically.
Other ingredients used for Muscle Tone (lack of)
adenosine 5-triphosphate disodium (ATP)alpha-ketoglutarate (AKG)
amino acids
ashwagandha
astaxanthin
beet
branched-chain amino acids
calcium
caterpillar mushroom
cissus quadrangularis
coenzyme Q10 (CoQ10)
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
fish protein
l-isoleucine
L-arginine
l-carnitine
L-citrulline
L-leucine
L-valine
maca
magnesium
ornithine alpha-ketoglutarate
phytocannabinoids
potassium
sardines
black ginger
tongkat ali
Urolithin A
vitamin D
whey protein
atractylodes
cistanche
electrolytes blend (proprietary)
camphor oil
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
Aralia
Arginine Alpha Ketoglutarate
Antler
Arginine Creatine
Alpha-ketoisocaproic acid
Algal protein
Alpha hydroxyisocaproic acid
Animal protein
Beef Protein
Beef
Beef liver
Bovine Protein
beta-lactoglobulin
Banyan
Ba Ji Tian
BCAA
Casein
Chinese Silkvine
Chinese Mountain Ant
Cyathula
Chuchuhuasi
Creatine
Chicken
Deer Velvet
Eurycomanone
Egg
Eurycoma Longifolia
Ecdysteroids
Ecdysterone
Egg protein
Fish
Guanidinoacetic acid
Ginsenosides
Hydroxymethylbutyrate
HMB Hydroxymethylbutyrate
Isoleucine
Legume protein
Mineral Blend
Maral Root
Marine Protein
Milk Protein
Methylxanthine
Phosphocreatine
Premna
Phytoecdysteroid
Phosphatidic Acid
Quinoa Protein
Safed musli
salt
Sida cordifolia
Shilajit
Turkesterone
Ursolic Acid
Withanolides
Xanthine
Xanthophyll
Other health conditions supported by L-valine
Athletic and Exercise AidsBody Building
Fatigue
Muscle Tone (lack of)
Products containing L-valine
Designs For Health
Amino Acid Supreme™
Designs For Health
Amino Acid Synergy
Thorne
Amino Complex Berry
Thorne
Amino Complex Lemon
Pure Encapsulations
Amino-NR
Pure Encapsulations
Amino Replete
Pure Encapsulations
BCAA
Pure Encapsulations
BCAA
Pure Encapsulations
BCAA
Designs For Health
BCAA Powder with L-Glutamine
Metagenics
BCAAs Orange Mango
Metagenics
BioPure Protein® Powder
Pure Encapsulations
Essential Aminos
Douglas Laboratories
Free Form Amino
Klean Athlete
Klean BCAA + Peak ATP®
Klean Athlete
Klean Essential Aminos + HMB®
Klean Athlete
Klean Isolate ™
Douglas Laboratories
Muscle Protect™ with HMB®
Metagenics
Perfect Protein® Pea & Rice Chocolate Powder
Metagenics
Perfect Protein Pea & Rice Vanilla Powder
Metagenics
Perfect Protein Whey Chocolate
Metagenics
Perfect Protein Whey Vanilla
Metagenics
Ultra Glucose Control® Chocolate
Metagenics
Ultra Glucose Control Chocolate
Metagenics
Ultra Glucose Control Vanilla
Metagenics
Ultra Glucose Control Vanilla
Metagenics
UltraGI Replenish® Chocolate
Metagenics
UltraGI Replenish Chocolate
Metagenics
UltraGI Replenish Vanilla
Metagenics
UltraGI Replenish Vanilla
Metagenics
UltraInflamX Plus 360°® Chocolate/Orange
Metagenics
UltraInflamX Plus 360° Mango
Metagenics
UltraInflamX Plus 360° Mango
Metagenics
UltraInflamX Plus 360° Orange
Metagenics
UltraInflamX Plus 360° Original Spice
Metagenics
UltraInflamX Plus 360° Pineapple/Banana
Metagenics
UltraInflamX Plus 360° Pineapple/Banana
Metagenics
UltraMeal Advanced Protein® Dutch Chocolate
Metagenics
UltraMeal Advanced Protein French Vanilla
Metagenics
UltraMeal Advanced Protein Plain
Metagenics
UltraMeal Cardio 360°® Pea/Rice Chocolate
Metagenics
UltraMeal Cardio 360° Pea/Rice Vanilla