Evidence supporting the use of: Magnesium citrate malate
For the health condition: Muscle Tone (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Magnesium citrate malate is a bioavailable form of magnesium, a mineral essential for normal muscle function. Scientific evidence supports the role of magnesium in muscle contraction and relaxation, as it acts as a cofactor in numerous enzymatic processes involved in neuromuscular transmission. Magnesium deficiency is associated with symptoms such as muscle cramps, weakness, and impaired muscle tone (hypotonia). Several studies have demonstrated that magnesium supplementation can help alleviate muscle cramps and improve muscle function, particularly in individuals who are deficient or at risk of deficiency (e.g., elderly, athletes, or those with certain medical conditions). However, the direct evidence specifically linking magnesium citrate malate (as opposed to other forms of magnesium) to improved muscle tone in non-deficient populations is limited. Most clinical trials focus on general magnesium supplementation rather than this specific salt.

Despite this, magnesium citrate malate is often preferred in supplements due to its good absorption and gastrointestinal tolerance. Thus, while there is a moderate level of scientific validation—primarily based on the known physiological role of magnesium and evidence from supplementation studies—the use of magnesium citrate malate specifically for supporting muscle tone receives a rating of 3 out of 5. It is best suited for individuals with or at risk for magnesium deficiency rather than as a universal remedy for muscle tone issues in the general population.

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