Serum protein, particularly in the form of whey or other high-quality dietary proteins, is scientifically validated as an effective means to support muscle tone, especially in individuals with reduced muscle mass or tone (such as in sarcopenia or muscle wasting conditions). Proteins are composed of essential amino acids, which are critical for muscle protein synthesis. Numerous randomized controlled trials and meta-analyses have demonstrated that dietary protein supplementation, including serum-derived proteins, can enhance muscle mass, strength, and functional outcomes when combined with resistance exercise, as well as in elderly or immobilized patients with muscle atrophy. The mechanism is primarily through the stimulation of muscle protein synthesis via the mTOR signaling pathway, and the provision of branched-chain amino acids such as leucine, which are abundant in serum proteins. Clinical guidelines for the management of sarcopenia and muscle wasting often recommend increased protein intake as a cornerstone of therapy. While serum protein is not a direct treatment for neurological causes of poor muscle tone (such as hypotonia from nerve damage), it is a validated nutritional intervention for supporting and restoring muscle mass and tone in conditions rooted in protein malnutrition or disuse. Thus, its use is well-supported by scientific evidence.