Evidence supporting the use of: Sterones (unspecified)
For the health condition: Muscle Tone (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Sterones is a broad term that generally refers to steroid hormones, a class that includes androgens (such as testosterone), anabolic steroids, corticosteroids, and others. The use of anabolic steroids in particular to support or treat lack of muscle tone (i.e., muscle weakness or hypotonia) is scientifically validated, especially in clinical contexts such as muscle wasting diseases (e.g., cachexia, certain muscular dystrophies) and in some cases of age-related sarcopenia. Numerous studies have demonstrated that anabolic steroids can increase muscle mass and improve muscle strength by promoting protein synthesis and inhibiting protein breakdown in muscle tissue. Testosterone replacement therapy is similarly used in hypogonadal men to improve muscle mass and tone. However, their use outside strictly controlled medical settings can carry significant risks and is not generally recommended for healthy individuals due to potential side effects. The evidence supporting their efficacy in improving muscle mass and strength is strong (rated 4/5), with most clinical guidelines reserving such treatment for specific medical indications. Use for general improvement of muscle tone in the absence of underlying disease is not supported by clinical guidelines and may be illegal or unsafe. The evidence is robust in clinical contexts, but risks and contraindications must be weighed carefully.

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