Evidence supporting the use of: Valine
For the health condition: Muscle Tone (lack of)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Valine is one of the three branched-chain amino acids (BCAAs), along with leucine and isoleucine, that are essential for human health and must be obtained through the diet. Scientific interest in valine and other BCAAs for muscle health is based on their role in protein synthesis and energy production during exercise. Several studies have explored the use of BCAAs in supporting muscle mass and recovery, especially in athletes and individuals with muscle-wasting conditions. However, the specific effect of valine alone—separate from the other BCAAs—on muscle tone is less well-established.
Most available research examines BCAA mixtures rather than isolated valine, and results are mixed. Some studies suggest that BCAA supplementation may help reduce exercise-induced muscle damage and promote muscle protein synthesis, which can indirectly support muscle tone, particularly in individuals experiencing muscle loss due to illness or aging. However, evidence for a direct effect of valine alone on improving muscle tone is limited. Furthermore, muscle tone refers not just to muscle mass but also to the continuous and passive partial contraction of muscles, and there is little direct evidence that valine supplementation specifically improves this aspect.
In summary, while there is a scientific rationale for the use of valine (as part of BCAAs) in muscle support, the evidence is modest and mostly indirect, with limited research focusing specifically on valine and the improvement of muscle tone.
Other ingredients used for Muscle Tone (lack of)
adenosine 5-triphosphate disodium (ATP)alpha-ketoglutarate (AKG)
amino acids
ashwagandha
astaxanthin
beet
branched-chain amino acids
calcium
caterpillar mushroom
cissus quadrangularis
coenzyme Q10 (CoQ10)
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
fish protein
l-isoleucine
l-arginine
l-carnitine
l-citrulline
l-leucine
l-valine
maca
magnesium
ornithine alpha-ketoglutarate
phytocannabinoids
potassium
sardines
black ginger
tongkat ali
Urolithin A
vitamin D
whey protein
atractylodes
cistanche
electrolytes blend (proprietary)
camphor oil
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
Aralia
Arginine Alpha Ketoglutarate
Antler
Arginine Creatine
Alpha-ketoisocaproic acid
Algal protein
Alpha hydroxyisocaproic acid
Animal protein
Beef Protein
Beef
Beef liver
Bovine Protein
beta-lactoglobulin
Banyan
Ba Ji Tian
BCAA
Casein
Chinese Silkvine
Chinese Mountain Ant
Cyathula
Chuchuhuasi
Creatine
Chicken
Deer Velvet
Egg
Ecdysteroids
Ecdysterone
Egg protein
Isoleucine
Milk Protein
Quinoa Protein
salt
Other health conditions supported by Valine
Athletic and Exercise AidsBody Building
Fatigue
Muscle Tone (lack of)