Evidence supporting the use of: 4-androsterone
For the body system: Muscles
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
4-Androsterone, often referred to as 4-andro or 4-androstene-3b-ol, 17-one, is a prohormone that serves as a precursor to testosterone and other androgens in the body. Its use in supporting the muscles body system is based on its potential to increase endogenous testosterone levels, which in turn may promote muscle growth, strength, and recovery. Some limited clinical and preclinical studies have shown that prohormones like 4-androsterone can be converted in vivo to active anabolic hormones, leading to mild increases in lean body mass and muscle protein synthesis. However, the evidence base is relatively weak, consisting mostly of animal studies, in vitro research, and anecdotal reports from athletes and bodybuilders. Large, well-controlled human trials are lacking, and the long-term safety profile of 4-androsterone supplementation remains unclear. Furthermore, the use of such prohormones is often regulated or prohibited by sports organizations due to their anabolic effects and potential for misuse. In summary, there is some limited scientific rationale for the use of 4-androsterone to support muscle function, but the quality and quantity of evidence is low, and caution is warranted due to potential risks and regulatory concerns.
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acetyl l-carnitineadenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
astaxanthin
beet
beta-alanine
bovine
bovine liver
branched-chain amino acids
bromelain
caffeine
calcium
cherry
chloride
coenzyme Q10 (CoQ10)
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
turmeric
d-alpha tocopherol
devil's claw
dong quai root
fish protein
forskohlii root
l-isoleucine
iron
kale
l-alanine
l-alanyl-l-glutamine
l-arginine
l-carnitine
l-carnosine
l-citrulline
l-glutamine
l-glycine
l-leucine
l-ornithine
l-proline
l-taurine
l-threonine
l-valine
magnesium
malic acid
maltodextrin
maltose
methylsulfonylmethane (MSM)
milk
nicotinamide riboside
ornithine alpha-ketoglutarate
peppermint oil
phosphorus
phytocannabinoids
potassium
protein
quinoa
rhizome
sardines
black ginger
soybean
specialized pro-resolving mediators (SPMs)
spinach
spirulina
tongkat ali
ubiquinol
Urolithin A
vitamin B
vitamin C
vitamin D
vitamin D3
water
watermelon
whey protein
white willow
β-nicotinamide mononucleotide (NMN)
suma
squawvine
sodium salt
solomon's seal
siler root
eucommia
electrolytes blend (proprietary)
guelder rose
polyphenols
trace minerals
wintergreen
camphor oil
menthol oil
wheat germ
wood betony
herbal blend (proprietary)
algae
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
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17a-di methyl-bol
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Animal Tissue
Antler
Arginine Creatine
Arginine nitrate
Arachidonic Acid
Arginine malate
Arginine aspartate
Avocado
Anserina
Alpha-ketoisocaproic acid
Acetylcholine
adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine alpha-ketoisocaproate
Arginine silicate
Animal protein
Blue Cohosh
Biopeptide
Beta-hydroxybutyrate
Bicarbonate
Beef Protein
Black galingale
Beef
Beef liver
Bovine Protein
Black Gram
Black willow
Ba Ji Tian
Bee products
banana
BCAA
Chia seed
Casein
Cardarine
Chinese Mountain Ant
Carnosine
Citrate malate
Cyathula
Curcuminoid
Cramp Bark
Chuchuhuasi
Cyanotis Vaga
Coca
Coconut Water
Cetylated Fatty Acids
Creatine
Chicken
Curcuma
C-Phycocyanin
Cyanotis arachnoides
DL-Methionine
Deer Velvet
Date
D-Ribose
Dextrose
Dimethyl sulfoxide (DMSO)
Dipsacus
Dipeptide
epicatechin
Epistane
Egg
Erythrina
Elk antler
Emu Oil
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Essential Oil Blend
Egg protein
fibroblast growth factor
glucose
Glycine
Isoleucine
Milk Protein
Phosphate Salt
Potash
Quinoa Protein
salt
Soy Protein