Evidence supporting the use of: Acetylcholine
For the body system: Muscles

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Acetylcholine is a neurotransmitter that plays a critical role in the functioning of the muscular system, particularly in the process of muscle contraction. It is the primary neurotransmitter released at neuromuscular junctions—the synapses between motor neurons and skeletal muscle fibers. When a nerve impulse reaches the neuromuscular junction, acetylcholine is released from the nerve ending and binds to receptors on the muscle fiber membrane (sarcolemma). This binding triggers a series of events that lead to muscle contraction. The role of acetylcholine in this process is well-established and foundational in human physiology and medical science, supported by extensive research and clinical observation.

Deficiencies or disruptions in acetylcholine signaling can result in serious muscular disorders, such as myasthenia gravis, where antibodies attack acetylcholine receptors, causing muscle weakness. Treatments for such disorders often aim to increase acetylcholine levels or enhance its action. Furthermore, the use of acetylcholine or cholinergic drugs is standard in pharmacology to influence muscle activity during certain medical procedures. Due to this comprehensive and robust scientific evidence, acetylcholine's use to support the muscular system is highly validated.

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Products containing Acetylcholine

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